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Found 5667 with Last Name = 'boys' and Initial = 'ml'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185450(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(5,6...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177621((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-thiomo...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177626(3-(benzo[d]oxazol-6-yl)-4-(3-(3-(5,6,7,8-tetrahydr...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185464(3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177628((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(5,6,7,8-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185466((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-...)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177626(3-(benzo[d]oxazol-6-yl)-4-(3-(3-(5,6,7,8-tetrahydr...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185459(3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(4,5-dihydro-...)
Affinity DataIC50:  0.580nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177629(3-(2-cyclopropylthiazol-5-yl)-4-(3-(3-(5,6,7,8-tet...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185460(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-(carboxymethyl)-...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178254(3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(1-methyl-1,2...)
Affinity DataIC50:  0.610nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177621((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-thiomo...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177618(3-(2,3-dihydrobenzofuran-6-yl)-4-(3-(3-(5,6,7,8-te...)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177628((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(5,6,7,8-...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177636(3-(quinolin-3-yl)-4-(3-(3-(5,6,7,8-tetrahydro-1,8-...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185469(3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(2-(1-methyl-1,2...)
Affinity DataIC50:  0.690nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185452(3-(benzo[d][1,3]dioxol-5-yl)-4-(5-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  0.710nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177616((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-morpho...)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185468(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(1-m...)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177622(3-(pyridin-3-yl)-4-(3-(3-(5,6,7,8-tetrahydro-1,8-n...)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185450(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(5,6...)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of alphavbeta5 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177616((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-morpho...)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185455(3-(6-methoxypyridin-3-yl)-4-(1-methyl-5-(2-(5,6,7,...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185462(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(5,6...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185465(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(1,2...)
Affinity DataIC50:  0.830nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185454(3-(6-methoxypyridin-3-yl)-4-(3-(2-(5,6,7,8-tetrahy...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185453(3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(1-methyl-5-(...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185457(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-benzyl-5-(2-(5,6...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185459(3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(3-(4,5-dihydro-...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185464(3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  1nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177640(3-(6-methoxypyridin-3-yl)-4-(3-(3-(5,6,7,8-tetrahy...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50382322(CHEMBL2024689)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50382321(CHEMBL2024688)
Affinity DataIC50:  1nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185471(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-(2-hydroxyethyl)...)
Affinity DataIC50:  1nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185470(3-(benzo[d][1,3]dioxol-5-yl)-4-(5-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  1.03nMAssay Description:Inhibition of alphavbeta5 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185470(3-(benzo[d][1,3]dioxol-5-yl)-4-(5-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  1.09nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177624(3-(3-fluorophenyl)-4-(3-(3-(5,6,7,8-tetrahydro-1,8...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Integrin alphav-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177627((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(4-(4-methox...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185450(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(5,6...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185472(3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(3-(2-(5,6,7,...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185463(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)
Affinity DataIC50:  1.18nMAssay Description:Inhibition of alphavbeta3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178253(3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(5,6,7,8-tetr...)
Affinity DataIC50:  1.18nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177629(3-(2-cyclopropylthiazol-5-yl)-4-(3-(3-(5,6,7,8-tet...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Integrin alphav-beta5 receptor expressed in HEK293 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50177617(3-(1-phenyl-1H-pyrazol-4-yl)-4-(3-(3-(5,6,7,8-tetr...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Integrin alphav-beta3 receptor by SPRA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185469(3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(2-(1-methyl-1,2...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185464(3-(benzo[d][1,3]dioxol-5-yl)-4-(3-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of alphavbeta5 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185452(3-(benzo[d][1,3]dioxol-5-yl)-4-(5-(2-(5,6,7,8-tetr...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178243(3-(2-(methoxymethyl)thiazol-5-yl)-4-(2-(3-(5,6,7,8...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185468(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-methyl-5-(2-(1-m...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of alphavbeta3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178245(3-(2-cyclopropylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tet...)
Affinity DataIC50:  1.22nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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