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Found 323 with Last Name = 'bray' and Initial = 'jd'
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415020(CHEMBL570708)
Affinity DataIC50:  2.51nMAssay Description:Agonist activity at progesterone receptor in human T47D cell after 24 hrs by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294706(4-((2-chlorobenzyl)(3-methyl-1-(1-methyl-1H-tetraz...)
Affinity DataIC50:  5nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304973((S)-4-((2-bromobenzyl)(1-(methylsulfonyl)pyrrolidi...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304972((S)-2-chloro-4-((2-chlorobenzyl)(1-(methylsulfonyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304987((S)-4-((2-bromobenzyl)(1-propionylpyrrolidin-3-yl)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298033((S)-ethyl 2-(3-((3-chloro-4-cyanophenyl)(2-chlorob...)
Affinity DataIC50:  8nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298032((S)-2-chloro-4-((2-chlorobenzyl)(1-(cyanomethyl)py...)
Affinity DataIC50:  8nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304978((S)-methyl 3-((3-chloro-4-cyanophenyl)(2-chloroben...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298207((S)-2-chloro-4-((2-chlorobenzyl)(1-isopropyl-5-oxo...)
Affinity DataIC50:  10nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298208((S)-2-chloro-4-((2-chloro-5-fluorobenzyl)(1-ethyl-...)
Affinity DataIC50:  10nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298210((S)-2-chloro-4-((2,5-dichlorobenzyl)(1-ethyl-5-oxo...)
Affinity DataIC50:  10nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304977((S)-methyl 3-((3-chloro-4-cyanophenyl)(2-methylben...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304975((S)-methyl 3-((3-chloro-4-cyanophenyl)(2-(trifluor...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304976((S)-methyl 3-((3-chloro-4-cyanophenyl)(2-fluoroben...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304964((S)-2-chloro-4-((1-(methylsulfonyl)pyrrolidin-3-yl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294705(4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)p...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298030((S)-2-chloro-4-((2-chlorobenzyl)(1-(3,3,3-trifluor...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294703(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294696(4-((2-chlorobenzyl)(1-(2-methylthiazol-4-yl)ethyl)...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294702(4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)e...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294715(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298219((R)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataIC50:  15nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298209((S)-2-chloro-4-((1-ethyl-5-oxopyrrolidin-3-yl)(2-m...)
Affinity DataIC50:  15nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304974((S)-2-chloro-4-((2-methylbenzyl)(1-(methylsulfonyl...)
Affinity DataIC50:  16nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294707(4-((2-chlorobenzyl)(1-(1-ethyl-1H-tetrazol-5-yl)et...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294710(2-chloro-4-(isobutyl(3-methyl-1-(1-methyl-1H-tetra...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298028((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataIC50:  16nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298028((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294714(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304957((S)-2-chloro-4-((2-methylbenzyl)(1-propionylpyrrol...)
Affinity DataIC50:  16nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294712((S)-2-chloro-4-((cyclobutylmethyl)(3-methyl-1-(1-m...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304980((S)-methyl 3-((3-chloro-4-cyanophenyl)(5-fluoro-2-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304979((S)-methyl 3-((3-chloro-4-cyanophenyl)(2,3-difluor...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304971((S)-2-chloro-4-((2-fluorobenzyl)(1-(methylsulfonyl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298029((S)-2-chloro-4-((2-chlorobenzyl)(1-isopropylpyrrol...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298211((S)-2-chloro-4-((1-isopropyl-5-oxopyrrolidin-3-yl)...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298043((S)-2-chloro-4-((2-chlorobenzyl)(1-methylpyrrolidi...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294699(4-((2-chlorobenzyl)(1-(3-methylisoxazol-5-yl)ethyl...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294700(4-((2-chlorobenzyl)(1-(1-methyl-1H-imidazol-2-yl)e...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298212((S)-2-chloro-4-((2-fluorobenzyl)(1-methyl-5-oxopyr...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298035((S)-2-chloro-4-((2-chlorobenzyl)(1-(pyridin-2-ylme...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304984((S)-2-chloro-4-((1-propionylpyrrolidin-3-yl)(2-(tr...)
Affinity DataIC50:  25nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304985((S)-2-chloro-4-((1-isobutyrylpyrrolidin-3-yl)(2-(t...)
Affinity DataIC50:  25nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294709(4-((2-(trifluoromethyl)benzyl)(3-methyl-1-(1-methy...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298031((S)-2-chloro-4-((2-chlorobenzyl)(1-(2-methoxyethyl...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294717(4-((2-chlorobenzyl)(3-methyl-1-(4-methyl-4H-1,2,4-...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304959((S)-2-chloro-4-((2,5-dichlorobenzyl)(1-propionylpy...)
Affinity DataIC50:  25nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298206((S)-2-chloro-4-((2-chlorobenzyl)(1-methyl-5-oxopyr...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298213((S)-2-chloro-4-((2,3-difluorobenzyl)(1-methyl-5-ox...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298214((S)-2-chloro-4-((1-methyl-5-oxopyrrolidin-3-yl)(2-...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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