TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase mutant (Tyr-181 to Cys)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase mutant (Tyr-181 to Cys)More data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase mutant (Tyr-181 to Leu)More data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Compound was tested in vitro for its binding affinity towards recombinant human Calcitonin gene-related peptide type receptor (membranes of HEK-293 c...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90E+3nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for ability to block the CD4-gp120 interaction measured by binding of [125I]-sCD4 to gp120More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Tested in an HIV viral syncytium assay for inhibition of binding of recombinant CD4-gp120More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >3.40E+4nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >3.40E+4nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >3.40E+4nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >3.40E+4nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >3.40E+4nMAssay Description:Inhibitory activity of the compound against human cytomegalovirus (HCMV) protease was evaluatedMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+4nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+4nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60E+4nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition of binding of soluble recombinant CD4-gp120 using ELISA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals R&D
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [125I]-hCGRP human Calcitonin gene-related peptide type receptor expressed in SK-N-MC neuroblastoma cell membranesMore data for this Ligand-Target Pair