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Found 61 with Last Name = 'brennan' and Initial = 't'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283355(CHEMBL311418 | {(S)-1-[3-(Benzyl-methyl-carbamoyl)...)
Affinity DataKi:  0.400nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283358(CHEMBL79799 | [(S)-1-(1-Benzyl-3-benzylcarbamoyl-3...)
Affinity DataKi:  1nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50037811(CHEMBL123016 | {(S)-1-[(S)-3-Benzylcarbamoyl-1-(4-...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity of the compound was determined against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50037811(CHEMBL123016 | {(S)-1-[(S)-3-Benzylcarbamoyl-1-(4-...)
Affinity DataKi:  5nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283362(CHEMBL311049 | {(S)-1-[1-(4-Benzyloxy-benzyl)-3,3-...)
Affinity DataKi:  5nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282534(CHEMBL21095 | {(S)-1-[1-(4-Benzyloxy-benzyl)-3-((R...)
Affinity DataKi:  8nMAssay Description:Inhibitory activity of the compound was determined against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283359(CHEMBL83002 | [(S)-1-(1-Benzyl-3,3-difluoro-4-morp...)
Affinity DataKi:  70nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012250(CHEMBL58947 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50282993((2S,4R)-4-Cyclohexyl-2-hydroxy-3-((R)-3-methylsulf...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012251(2-{2-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-he...)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  0.280nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012249(CHEMBL58256 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  0.680nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006202(3-Amino-N-[1-[1-(1-cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012257(CHEMBL299252 | N-[1-Cyclohexylmethyl-3,3-difluoro-...)
Affinity DataIC50:  0.790nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM17941((2S,4S,5S)-5-[(2S)-2-[(2S)-2-benzyl-3-[(2-methylpr...)
Affinity DataIC50:  0.830nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012252(CHEMBL57492 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  0.950nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282525(CHEMBL283537 | {(S)-1-[1-(4-Benzyloxy-benzyl)-3-((...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012247(4-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282527(CHEMBL280358 | {(S)-1-[1-(4-Benzyloxy-benzyl)-3-((...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283364(CHEMBL314234 | {(S)-1-[1-(4-Benzyloxy-benzyl)-4-(3...)
Affinity DataIC50:  2nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282526(CHEMBL20642 | {(S)-1-[1-(4-Benzyloxy-benzyl)-3,3-d...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012255(CHEMBL293328 | N-[1-Cyclohexylmethyl-2-hydroxy-3-(...)
Affinity DataIC50:  4nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282538((R)-2-[4-((S)-2-Benzyloxycarbonylamino-3-methyl-bu...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282529(CHEMBL19752 | {(S)-1-[(R)-1-(4-Benzyloxy-benzyl)-3...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282535(CHEMBL19973 | {(S)-1-[1-(4-Benzyloxy-benzyl)-3,3-d...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282537(CHEMBL264739 | {(S)-1-[1-(4-Benzyloxy-benzyl)-3,3-...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282528((R)-2-[4-((S)-2-Benzyloxycarbonylamino-3-methyl-bu...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283357(CHEMBL82829 | {[3-Benzylcarbamoyl-1-(4-benzyloxy-b...)
Affinity DataIC50:  6nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282531(CHEMBL278084 | {(S)-1-[(S)-1-(4-Benzyloxy-benzyl)-...)
Affinity DataIC50:  6.60nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283361(5-(4-Benzyloxy-phenyl)-2,2-difluoro-4-[(S)-3-methy...)
Affinity DataIC50:  8nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282530(CHEMBL20135 | {(S)-1-[1-(4-Benzyloxy-benzyl)-3,3-d...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283356(CHEMBL309464 | {(S)-1-[3-Benzylcarbamoyl-1-(4-benz...)
Affinity DataIC50:  15nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283354(CHEMBL79345 | {(S)-1-[3-(Benzyl-ethyl-carbamoyl)-1...)
Affinity DataIC50:  15nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012253(CHEMBL56982 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50282993((2S,4R)-4-Cyclohexyl-2-hydroxy-3-((R)-3-methylsulf...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration on Bovine Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012254(CHEMBL60535 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012250(CHEMBL58947 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012247(4-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  36nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282532(CHEMBL280398 | {(S)-1-[1-(4-Benzyloxy-benzyl)-3-((...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012249(CHEMBL58256 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  43nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012246(CHEMBL58153 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283363(CHEMBL312809 | {(S)-1-[1-Benzyl-4-(3,4-dihydro-1H-...)
Affinity DataIC50:  50nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50282533(CHEMBL262702 | {(R)-1-[1-(4-Benzyloxy-benzyl)-3-((...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity was determined against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283353(CHEMBL81135 | {[3-Benzylcarbamoyl-1-(4-benzyloxy-b...)
Affinity DataIC50:  70nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012252(CHEMBL57492 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50: >100nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012253(CHEMBL56982 | N-(1-Cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Bovine Cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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