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Found 16 with Last Name = 'bridges' and Initial = 'k'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50370424(CHEMBL1791292)
Affinity DataKi:  1.10E+4nMAssay Description:In vitro inhibitory concentration against Protein-tyrosine phosphatase 1B hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50370425(CHEMBL1791291)
Affinity DataKi:  1.80E+4nMAssay Description:In vitro inhibitory concentration against Protein-tyrosine phosphatase 1B hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50153248(CHEMBL183738 | N-acetyl-Asp-{5-(2-Amino-2-carboxy-...)
Affinity DataKi:  4.10E+4nMAssay Description:In vitro inhibitory concentration against Protein-tyrosine phosphatase 1B hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148338(4-[((S)-2-{(3S,4S)-4-[(3S,4S)-4-((S)-2-Acetylamino...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148337(4-[((S)-2-{(3S,4S)-4-[(3S,4S)-4-((S)-2-Acetylamino...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148337(4-[((S)-2-{(3S,4S)-4-[(3S,4S)-4-((S)-2-Acetylamino...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50127427((S)-4-[(S)-2-((S)-2-{(S)-4-[2-((1S,2S)-2-Acetylami...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148346(4-[((S)-2-{(S)-4-[(3S,4S)-4-((S)-2-Acetylamino-4-m...)
Affinity DataIC50:  460nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148344(4-[((S)-2-{(3S,4S)-4-[(3S,4S)-4-((S)-2-Acetylamino...)
Affinity DataIC50:  650nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148340(4-{[(S)-2-((2S,4S)-5-Cyclohexyl-3-hydroxy-4-{(3S,4...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148343(4-[((S)-2-{(1S,5S)-4-[(2S,4S)-4-((S)-2-Acetylamino...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148341(4-[((S)-2-{(3S,4S)-4-[(3S,4S)-4-(2-Acetylamino-ace...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148347(4-[((S)-2-{(S)-4-[(3S,4S)-4-((S)-2-Acetylamino-4-m...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148345(4-[((S)-2-{(1S,5S)-4-[(2S,4S)-4-((S)-2-Acetylamino...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148339(4-({(S)-2-[(2S,4S)-4-((3S,4S)-4-tert-Butoxycarbony...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50148342(4-({(S)-2-[(2S,4S)-4-((3S,4S)-4-Amino-3-hydroxy-5-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed