Compile Data Set for Download or QSAR
maximum 50k data
Found 126 with Last Name = 'brinkman' and Initial = 'ja'
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity towards Dipeptidyl peptidase IV (DPP-IV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129897(1-(2-Amino-3-methyl-butyryl)-pyrrolidine-2-carboni...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129889(1-[2-(3-Hydroxy-adamantan-1-ylamino)-acetyl]-pyrro...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) obtained from rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129889(1-[2-(3-Hydroxy-adamantan-1-ylamino)-acetyl]-pyrro...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) obtained from human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  2.80nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) obtained from rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129945(1-[2-(Adamantan-1-ylamino)-acetyl]-pyrrolidine-2-c...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  3.15nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) obtained from human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129889(1-[2-(3-Hydroxy-adamantan-1-ylamino)-acetyl]-pyrro...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129884(6-{4-[2-(2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11113(6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from rat plasma.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11113(6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP IV) obtained from rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11113(6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP IV) obtained from human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129868(1-{2-[4-(5-Trifluoromethyl-pyridin-2-ylamino)-cycl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129865(1-[2-(3-Ethyl-adamantan-1-ylamino)-acetyl]-pyrroli...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11113(6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from human plasma.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50:  8.70nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50:  8.73nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP IV) obtained from human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288129((2-Phenyl-propyl)-{2-[4-((E)-styryl)-phenoxy]-ethy...)
Affinity DataIC50:  9nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288124(Benzyl-{2-[4-((E)-styryl)-phenoxy]-ethyl}-amine | ...)
Affinity DataIC50:  9nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129898(1-{2-[4-(Benzothiazol-2-ylamino)-cyclohexylamino]-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288127(CHEMBL312125 | [2-(4-Benzyloxy-phenoxy)-ethyl]-(2-...)
Affinity DataIC50:  10nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129909(1-[2-(Adamantan-2-ylamino)-acetyl]-pyrrolidine-2-c...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129925(1-{2-[4-(4-Chloro-phenoxy)-cyclohexylamino]-acetyl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288123(CHEMBL82277 | [2-(4-Benzyloxy-phenoxy)-ethyl]-phen...)
Affinity DataIC50:  15nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129912(1-[2-(Bicyclo[2.2.1]hept-2-ylamino)-acetyl]-pyrrol...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129900((1R,2R,3R,5S)1-[2-(2,6,6-Trimethyl-bicyclo[3.1.1]h...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129943(1-[2-(3,5-Dimethyl-adamantan-1-ylamino)-acetyl]-py...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50:  17.3nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP IV) obtained from rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129926(CHEMBL92021 | Cyclohexanecarboxylic acid {4-[2-(2-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129872(CHEMBL319115 | tert-Butyl-carbamic acid 3-[2-(2-cy...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11113(6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from Caco-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM11113(6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129908(1-[2-(1-Cyclohexanecarbonyl-piperidin-4-ylamino)-a...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129924(1-[2-(1,1-Dimethyl-2-phenyl-ethylamino)-acetyl]-py...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129915(1-[2-(1-Hydroxymethyl-cyclopentylamino)-acetyl]-py...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129902(6-{2-[2-(2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129937(1-{2-[2-(Pyridin-2-ylamino)-ethylamino]-acetyl}-py...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM12644((2S)-1-[2-(tert-butylamino)acetyl]pyrrolidine-2-ca...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129940(1-{2-[2-(5-Chloro-pyridin-2-ylamino)-ethylamino]-a...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129881(1-(2-Cyclooctylamino-acetyl)-pyrrolidine-2-carboni...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM12645((2S)-1-[2-(cyclopentylamino)acetyl]pyrrolidine-2-c...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50288128(Benzyl-(4-benzyloxy-benzyl)-amine | CHEMBL82015)
Affinity DataIC50:  55nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50129919(CHEMBL330689 | Phenyl-carbamic acid 3-[2-(2-cyano-...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 126 total ) | Next | Last >>
Jump to: