Compile Data Set for Download or QSAR
maximum 50k data
Found 8 with Last Name = 'brongel' and Initial = 'k'
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  100nMAssay Description:Binding affinity to CDK2More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of p60 c-SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)
Affinity DataKd:  700nMAssay Description:Binding affinity to human wild type Mdm2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50272597((trans-2-(4-chlorobenzyl)-3-(4-chlorophenyl)-1-oxo...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human wild type Mdm2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50272597((trans-2-(4-chlorobenzyl)-3-(4-chlorophenyl)-1-oxo...)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to human wild type Mdm2 by NMR ligand-protein binary titrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50272597((trans-2-(4-chlorobenzyl)-3-(4-chlorophenyl)-1-oxo...)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to human wild type Mdm2 by NMR ligand-protein binary titrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed