Affinity DataKi: 3nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 11.5nM ΔG°: -45.3kJ/molepH: 7.5 T: 2°CAssay Description:The oxidation of NADPH was monitored at 340 nm using a Molecular Devices SpectraMax Plus 96-well microtiter plate reading spectrophotometer. Plots we...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Competitive inhibition of Acetyltransferase activity of Escherichia coli BL21(DE3) GlmU in presence of AcCoAMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Competitive inhibition of Acetyltransferase activity of Escherichia coli BL21(DE3) GlmU in presence of AcCoAMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
Affinity DataKi: 404nMAssay Description:Competitive inhibition of Acetyltransferase activity of Escherichia coli BL21(DE3) GlmU in presence of AcCoAMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
Affinity DataIC50: 302nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 600nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair