TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.310nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.354nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.650nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.75nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalpha expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human GlyT1a after 15 minsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human GlyT1a after 15 minsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human GlyT1a after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalpha expressed in 293T cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human GlyT1a after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 11.9nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor alpha expressed in 293T cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:In vitro concentration required to inhibit [3H]-estradiol binding to human estrogen receptor beta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14.3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15.1nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbeta expressed in 293T cellsMore data for this Ligand-Target Pair