Compile Data Set for Download or QSAR
maximum 50k data
Found 27 with Last Name = 'brown' and Initial = 'vh'
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50010932((10-DA, 10-Deazaminopterin)2-{4-[2-(2,4-Diamino-pt...)
Affinity DataKi:  0.00210nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | AMINOPTE...)
Affinity DataKi:  0.00230nMAssay Description:Tested for inhibition of dihydrofolate reductase enzyme from mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50025009(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-1-methyl-ethyl...)
Affinity DataKi:  0.00240nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50028641(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-1,1-dimethyl-e...)
Affinity DataKi:  0.00260nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50004544(2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-propyl]-...)
Affinity DataKi:  0.00280nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00320nMAssay Description:Tested for inhibition of dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
TargetThymidylate synthase(Escherichia coli)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022390(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pter...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against thymidylate synthase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022388(2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022388(2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022388(2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022388(2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022386(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022386(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022385(2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022385(2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  8.60E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022385(2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022385(2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022386(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022386(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...)
Affinity DataIC50:  3.40E+5nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed