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Found 13 with Last Name = 'browning' and Initial = 'm'
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400098(CHEMBL2178422)
Affinity DataKi:  0.0270nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400099(CHEMBL2178420)
Affinity DataKi:  0.0660nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388882(CHEMBL2063115)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382794(CHEMBL2023191)
Affinity DataKi:  0.0710nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400102(CHEMBL2178424)
Affinity DataKi:  0.0810nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400100(CHEMBL2178421)
Affinity DataKi:  0.670nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400101(CHEMBL2178423)
Affinity DataKi:  4.30nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cells after 2 hrs by gamma scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388881(CHEMBL2063116)
Affinity DataKi:  940nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388882(CHEMBL2063115)
Affinity DataIC50:  0.220nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50400098(CHEMBL2178422)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using benzoylresorufin as substrate after 45 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50400098(CHEMBL2178422)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-benzyloxy-4-trifluoromethylcoumarin as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400098(CHEMBL2178422)
Affinity DataEC50:  0.140nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production preincubated for 15 mins prior ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed