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Found 38 with Last Name = 'brubaker' and Initial = 'an'
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  10nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  17nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  17nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  20nMAssay Description:Compound was tested for its ability to inhibit crude aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022179((3-Oxo-3H-benzo[f]chromen-1-yl)-acetic acid | CHEM...)
Affinity DataIC50:  20nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022185((2-Oxo-2H-benzo[h]chromen-4-yl)-acetic acid | CHEM...)
Affinity DataIC50:  140nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022182((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid | 7-...)
Affinity DataIC50:  150nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022174((7-Ethyl-2-oxo-2H-chromen-4-yl)-acetic acid | CHEM...)
Affinity DataIC50:  240nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022183((5,7-Dihydroxy-2-oxo-2H-chromen-4-yl)-acetic acid ...)
Affinity DataIC50:  260nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022173((7-methoxy-2-oxo-2H-chromen-4-yl)acetic acid | 7-M...)
Affinity DataIC50:  370nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022247((4-Methyl-6-nitro-2-oxo-2H-quinolin-1-yl)-acetic a...)
Affinity DataIC50:  450nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022171((7-Chloro-2-oxo-2H-chromen-4-yl)-acetic acid | CHE...)
Affinity DataIC50:  560nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022175((2-Oxo-2H-chromen-4-yl)-acetic acid | CHEMBL274190)
Affinity DataIC50:  600nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022249((6-Methoxy-2-oxo-2H-quinolin-1-yl)-acetic acid | C...)
Affinity DataIC50:  910nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM16415((1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022181(3-(7-Methoxy-2-oxo-2H-chromen-4-yl)-propionic acid...)
Affinity DataIC50:  2.10E+3nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022252((6-Hydroxy-2-oxo-2H-quinolin-1-yl)-acetic acid | C...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022245((8-Hydroxy-2-oxo-2H-quinolin-1-yl)-acetic acid | C...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022187(3-(7-Methoxy-2-oxo-2H-chromen-4-yl)-acrylic acid |...)
Affinity DataIC50:  4.40E+3nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022246((4-Methyl-2-oxo-2H-quinolin-1-yl)-acetic acid | CH...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022184(7,8-Dihydroxy-4-methyl-2H-chromen-2-one (3) | 7,8-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022177(2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetamide | CH...)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022188(7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CH...)
Affinity DataIC50:  1.10E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022180(5,7-Dihydroxy-4-methyl-2H-chromen-2-one (2) | 5,7-...)
Affinity DataIC50:  1.70E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022186(1-naphthaleneacetic acid | 1-naphthylacetic acid |...)
Affinity DataIC50:  3.20E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022186(1-naphthaleneacetic acid | 1-naphthylacetic acid |...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022250(2-(8-Hydroxy-2-oxo-2H-quinolin-1-yl)-propionic aci...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022134(4-(6,7-Dimethoxy-4-oxo-3,4-dihydro-quinazolin-2-yl...)
Affinity DataIC50:  3.40E+4nMAssay Description:Compound was tested for its ability to inhibit crude aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022172((7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid meth...)
Affinity DataIC50:  3.80E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (uncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022137(4-(4-Oxo-3,4-dihydro-quinazolin-2-ylamino)-benzoic...)
Affinity DataIC50:  5.00E+4nMAssay Description:Compound was tested for its ability to inhibit crude aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022136(2-Hydroxy-4-(4-oxo-3,4-dihydro-quinazolin-2-ylamin...)
Affinity DataIC50:  5.70E+4nMAssay Description:Compound was tested for its ability to inhibit crude aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022176((7-Acetoxy-2-oxo-2H-chromen-4-yl)-acetic acid | CH...)
Affinity DataIC50:  6.10E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 4-methylumbelliferone...)
Affinity DataIC50:  6.20E+4nMAssay Description:Compound was tested for inhibitory concentration against rat lens aldose reductase (noncompetitive inhibition type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022133(2-(4-Hydroxy-phenylamino)-3H-quinazolin-4-one: 0.1...)
Affinity DataIC50:  7.50E+4nMAssay Description:Compound was tested for its ability to inhibit crude aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022251(3-(4-Methyl-2-oxo-2H-quinolin-1-yl)-propionic acid...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022135(4-(2-Methyl-4-oxo-4H-quinazolin-3-yl)-benzoic acid...)
Affinity DataIC50:  2.14E+5nMAssay Description:Compound was tested for its ability to inhibit crude aldose reductase obtained from rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022248(2-(4-Methyl-2-oxo-2H-quinolin-1-yl)-propionic acid...)
Affinity DataIC50:  4.70E+5nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022244(2-(6-Methoxy-2-oxo-2H-quinolin-1-yl)-propionic aci...)
Affinity DataIC50:  5.90E+5nMAssay Description:Inhibition of crude aldose reductase of rat lensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed