Compile Data Set for Download or QSAR
maximum 50k data
Found 76 with Last Name = 'brunetti' and Initial = 'm'
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110121(3-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110117(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{3...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110122((S)-4-((S)-2-Acetylamino-3-carboxy-propionylamino)...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110120(3-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  2nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110126(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{3...)
Affinity DataKi:  7nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110125(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  30nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50084685(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{3...)
Affinity DataKi:  40nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110123(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  100nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110124(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-(1...)
Affinity DataKi:  150nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110128(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-(1...)
Affinity DataKi:  600nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110127(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  640nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110118(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  700nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110119(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-(3...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349262(CHEMBL1807225 | CHEMBL1813106)
Affinity DataIC50:  4nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349262(CHEMBL1807225 | CHEMBL1813106)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350335(CHEMBL1813107)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350339(CHEMBL1813111)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350339(CHEMBL1813111)
Affinity DataIC50:  7nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350338(CHEMBL1813110)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350339(CHEMBL1813111)
Affinity DataIC50:  9nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349259(CHEMBL1807222 | CHEMBL1813105)
Affinity DataIC50:  12nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349259(CHEMBL1807222 | CHEMBL1813105)
Affinity DataIC50:  12nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350342(CHEMBL1813114)
Affinity DataIC50:  13nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349268(CHEMBL1807231 | CHEMBL1813109)
Affinity DataIC50:  15nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349262(CHEMBL1807225 | CHEMBL1813106)
Affinity DataIC50:  15nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350335(CHEMBL1813107)
Affinity DataIC50:  16nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350342(CHEMBL1813114)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349268(CHEMBL1807231 | CHEMBL1813109)
Affinity DataIC50:  18nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349268(CHEMBL1807231 | CHEMBL1813109)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350338(CHEMBL1813110)
Affinity DataIC50:  18nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350341(CHEMBL1813113)
Affinity DataIC50:  19nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50:  21nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349266(CHEMBL1807229 | CHEMBL1813108)
Affinity DataIC50:  21nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350335(CHEMBL1813107)
Affinity DataIC50:  22nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350342(CHEMBL1813114)
Affinity DataIC50:  22nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350341(CHEMBL1813113)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349259(CHEMBL1807222 | CHEMBL1813105)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350338(CHEMBL1813110)
Affinity DataIC50:  32nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349297(CHEMBL1808456 | CHEMBL1813104)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349266(CHEMBL1807229 | CHEMBL1813108)
Affinity DataIC50:  42nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349297(CHEMBL1808456 | CHEMBL1813104)
Affinity DataIC50:  42nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50:  42nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50:  48nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50:  48nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350341(CHEMBL1813113)
Affinity DataIC50:  60nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349297(CHEMBL1808456 | CHEMBL1813104)
Affinity DataIC50:  68nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50:  70nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50350331(CHEMBL1813103)
Affinity DataIC50:  77nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349266(CHEMBL1807229 | CHEMBL1813108)
Affinity DataIC50:  89nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50349282(CHEMBL1808284 | CHEMBL1813096)
Affinity DataIC50:  95nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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