TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 0.940nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidneyMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:The compound was tested for the ability to displace delta-receptor specific radioligand [3H]DSLETMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:The compound was tested for the ability to displace opioid receptor delta specific radioligand [3H]-DSLETMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:The compound was tested for the ability to displace delta-receptor specific radioligand [3H]DSLETMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:The compound was tested for the ability to displace delta-receptor specific radioligand [3H]DSLETMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Compound was tested for inhibition of hog kidney reninMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 7.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 9.40nMAssay Description:The compound was tested for the ability to displace Opioid receptor mu 1 specific radioligand [3H]DAGOMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of LVP-sensitive adenylate cyclase in a pig renal medullary preparationMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]naloxoneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:The compound was tested for the ability to displace Opioid receptor mu 1 specific radioligand [3H]DAGOMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:The compound was tested for the ability to displace receptor specific radioligand [3H]DPDPEMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:The compound was tested for the ability to displace mu-receptor specific radioligand [3H]DAGOMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]naloxoneMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories
Curated by ChEMBL
Smith Kline And French Laboratories
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair