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Found 30 with Last Name = 'buchmueller' and Initial = 'a'
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344969(CHEMBL1778340 | [(4R,6S)-8-Chloro-6-(2,3-dimethoxy...)
Affinity DataIC50:  56nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344972(1-{2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxy-phenyl)-1-...)
Affinity DataIC50:  112nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344971((1-{2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxy-phenyl)-1...)
Affinity DataIC50:  131nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344970(2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxy-phenyl)-1-iso...)
Affinity DataIC50:  162nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50118897((1-{2-[1-(3-Acetoxy-2,2-dimethyl-propyl)-7-chloro-...)
Affinity DataIC50:  213nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339917(1-(2-((1R,5R)-7-chloro-5-(2,3-dimethoxyphenyl)-1-i...)
Affinity DataIC50:  220nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344973(2-((3R,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-(3-h...)
Affinity DataIC50:  223nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50118898((1-{2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hydr...)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339916(CHEMBL1761660 | trans-rac-7-chloro-1-isobutyl-5-(2...)
Affinity DataIC50:  370nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339918(CHEMBL1761662 | trans-rac-1-(2-(7-chloro-5-(2,3-di...)
Affinity DataIC50:  450nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339919(CHEMBL1761661 | trans-rac-1-(2-(7-chloro-1-isobuty...)
Affinity DataIC50:  500nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339920(CHEMBL1761659 | trans-rac-1-(2-(7-chloro-5-(2-chlo...)
Affinity DataIC50:  930nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339921(CHEMBL1761656 | trans-rac-2-(7-chloro-5-(2,3-dimet...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339922(CHEMBL1761658 | trans-rac-2-(1-(2-(7-chloro-5-(2-c...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344968(CHEMBL1777819 | [(4S,6R)-8-Chloro-6-(2,3-dimethoxy...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339923(CHEMBL1761655 | trans-rac-2-(5-(2-methoxyphenyl)-7...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339924(CHEMBL1761654 | trans-rac-2-(5-(2-bromophenyl)-7-c...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339925(CHEMBL1761657 | trans-rac-6-(2-(7-chloro-5-(2-chlo...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339926(CHEMBL1761645 | trans-rac-2-(7-chloro-5-(2-chlorop...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344968(CHEMBL1777819 | [(4S,6R)-8-Chloro-6-(2,3-dimethoxy...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344968(CHEMBL1777819 | [(4S,6R)-8-Chloro-6-(2,3-dimethoxy...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339927(CHEMBL1761650 | trans-rac-2-(7-chloro-5-(2-chlorop...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339928(CHEMBL1761653 | trans-rac-2-(7-chloro-1-isobutyl-2...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339913(CHEMBL1761646 | trans-rac-ethyl 2-(7-chloro-5-(2-c...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339912(1-(2-((1S,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-i...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339911(CHEMBL1761652 | trans-rac-2-(1-benzyl-7-chloro-5-(...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339910(CHEMBL1761651 | trans-rac-2-(7-chloro-5-(2-chlorop...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339909(CHEMBL1761649 | trans-rac-2-(5-(2-chlorophenyl)-1-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339914(CHEMBL1761647 | trans-rac-2-(5-(2-chlorophenyl)-1-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339915(CHEMBL1761648 | trans-rac-2-(5-(2-chlorophenyl)-7-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed