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Found 16 with Last Name = 'bulteau-pignoux' and Initial = 'l'
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139822(10-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; ch...)
Affinity DataEC50:  1.41E+5nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139826(10-Chloro-6-hydroxy-5-propyl-pyrido[1,2-a]quinolin...)
Affinity DataEC50:  5.42E+4nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139824(7-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chl...)
Affinity DataEC50:  1.46E+5nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139824(7-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chl...)
Affinity DataEC50: >2.00E+5nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139825(5-Butyl-10-chloro-6-hydroxy-pyrido[1,2-a]quinoliny...)
Affinity DataEC50:  3.40E+4nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139826(10-Chloro-6-hydroxy-5-propyl-pyrido[1,2-a]quinolin...)
Affinity DataEC50:  4.80E+4nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139822(10-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; ch...)
Affinity DataEC50: >2.00E+5nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139827(5-Butyl-7-chloro-6-hydroxy-pyrido[1,2-a]quinolinyl...)
Affinity DataEC50:  750nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139827(5-Butyl-7-chloro-6-hydroxy-pyrido[1,2-a]quinolinyl...)
Affinity DataEC50:  1.70E+3nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139828(10-Chloro-6-hydroxy-5-pentyl-pyrido[1,2-a]quinolin...)
Affinity DataEC50:  2.10E+4nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139828(10-Chloro-6-hydroxy-5-pentyl-pyrido[1,2-a]quinolin...)
Affinity DataEC50:  2.00E+4nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139829(5-Ethoxycarbonyl-10-fluoro-6-hydroxy-pyrido[1,2-a]...)
Affinity DataEC50:  9.50E+4nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139823(10-Chloro-6-hydroxy-5-isobutyl-pyrido[1,2-a]quinol...)
Affinity DataEC50:  2.60E+4nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139829(5-Ethoxycarbonyl-10-fluoro-6-hydroxy-pyrido[1,2-a]...)
Affinity DataEC50:  7.05E+4nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139825(5-Butyl-10-chloro-6-hydroxy-pyrido[1,2-a]quinoliny...)
Affinity DataEC50:  2.35E+4nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50139823(10-Chloro-6-hydroxy-5-isobutyl-pyrido[1,2-a]quinol...)
Affinity DataEC50:  3.20E+4nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 microM FskMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed