Compile Data Set for Download or QSAR
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Found 47 with Last Name = 'bunce' and Initial = 'ra'
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50335530((S)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-d...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294211(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-3-hydroxy...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50336512((R)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-d...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM18070(5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)me...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM18070(5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)me...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50336514((S)-Iclaprim | CHEMBL1673303)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50336513((R)-Iclaprim | 5-[[(2R)-2-cyclopropyl-7,8-dimethox...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50335530((S)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-d...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50335530((S)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-d...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294211(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-3-hydroxy...)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294211(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-3-hydroxy...)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50336512((R)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-d...)
Affinity DataIC50:  11.5nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50336512((R)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-d...)
Affinity DataIC50:  11.5nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  14.4nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Bacillus anthracis DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Bacillus anthracis DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50335531(1-propyl-2-acryloyl-1,2-dihydrophthalazine | CHEMB...)
Affinity DataIC50:  46nMAssay Description:Inhibition of Bacillus anthracis DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus anthracis)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50335530((S)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-d...)
Affinity DataIC50:  54nMAssay Description:Inhibition of Bacillus anthracis DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50298821((S)-5-(3-(2-methoxy-2',6'-dimethylbiphenyl-4-yl)bu...)
Affinity DataIC50:  61nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM25826(5-[(3R)-3-(3-methoxy-5-phenylphenyl)but-1-yn-1-yl]...)
Affinity DataIC50:  61nMAssay Description:Inhibition of Staphylococcus aureus wild type recombinant DHFR by MTS assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50335532((E)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-d...)
Affinity DataIC50:  96nMAssay Description:Inhibition of Bacillus anthracis DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus anthracis)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50335533((E)-1-(1-butylphthalazin-2(1H)-yl)-3-(5-((2,4-diam...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Bacillus anthracis DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bacillus anthracis)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of Bacillus anthracis DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50095890(2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperaz...)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of Bacillus anthracis DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50335530((S)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-d...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294211(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-3-hydroxy...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539104(CHEMBL4641260)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539105(CHEMBL4636437)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539106(CHEMBL4643799)
Affinity DataKd:  5.40E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539107(CHEMBL4639280)
Affinity DataKd:  700nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539108(CHEMBL4649247)
Affinity DataKd:  300nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539109(CHEMBL4634383)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539121(CHEMBL4646130)
Affinity DataKd:  500nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539111(CHEMBL4646109)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539112(CHEMBL4647600)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539113(CHEMBL4649123)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539114(CHEMBL4634892)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539115(CHEMBL4635080)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539116(CHEMBL4648147)
Affinity DataKd:  2.30E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539117(CHEMBL4648396)
Affinity DataKd:  700nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539118(CHEMBL4643228)
Affinity DataKd:  2.30E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539119(CHEMBL4635630)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539120(CHEMBL4642813)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539103(CHEMBL4636754)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539102(CHEMBL7075)
Affinity DataKd:  600nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539110(CHEMBL4634635)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed