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Found 128 with Last Name = 'burgdorf' and Initial = 'l'
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553821(CHEMBL4741134)
Affinity DataIC50:  13nMAssay Description:Inhibition of ERK3 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553821(CHEMBL4741134)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553821(CHEMBL4741134)
Affinity DataIC50:  33nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553819(CHEMBL4755149)
Affinity DataIC50:  38nMAssay Description:Inhibition of ERK3 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553820(CHEMBL4786970)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553820(CHEMBL4786970)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553822(CHEMBL4757911)
Affinity DataIC50:  55nMAssay Description:Inhibition of ERK3 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553821(CHEMBL4741134)
Affinity DataIC50:  55nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553819(CHEMBL4755149)
Affinity DataIC50:  73nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553819(CHEMBL4755149)
Affinity DataIC50:  78nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340266(7-(2-(3-(4-chloro-2-methoxy-5-(trifluoromethyl)phe...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553819(CHEMBL4755149)
Affinity DataIC50:  93nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340264(7-(2-(3-(5-chloro-2-methoxy-4-methylphenyl)ureido)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553820(CHEMBL4786970)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340262(7-(2-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureid...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553822(CHEMBL4757911)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553816(CHEMBL4784697)
Affinity DataIC50:  138nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340273(CHEMBL1760633 | N-(6-(2-(3-(4-chloro-3-(trifluorom...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553816(CHEMBL4784697)
Affinity DataIC50:  143nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553817(CHEMBL4740226)
Affinity DataIC50:  157nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553817(CHEMBL4740226)
Affinity DataIC50:  158nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340259(7-(2-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553820(CHEMBL4786970)
Affinity DataIC50:  165nMAssay Description:Inhibition of ERK3 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340270(CHEMBL1760630 | N-(6-(2-(3-(2-methoxy-5-(trifluoro...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553822(CHEMBL4757911)
Affinity DataIC50:  177nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340285(CHEMBL1760736 | N-(6-(2-(3-(2-(2-aminoethoxy)-4-ch...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340265(7-(2-(3-(4-chloro-2-methoxy-5-methylphenyl)ureido)...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340277(CHEMBL1760637 | N-(6-(2-(3-(5-chloro-2-methoxy-4-m...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340288(CHEMBL1760617 | N-methyl-7-(2-(3-(3-(trifluorometh...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340258(CHEMBL1760619 | N-methyl-7-(2-(3-(4-methyl-3-(trif...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340281(CHEMBL1760641 | N-(6-(2-(3-(2-(2-(methylamino)etho...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553816(CHEMBL4784697)
Affinity DataIC50:  227nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340282(CHEMBL1760642 | N-(6-(2-(3-(4-chloro-2-(2-(methyla...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340290(CHEMBL1760737 | N-(6-(2-(3-(2-(pyrrolidin-2-ylmeth...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340260(7-(2-(3-(4-fluoro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553822(CHEMBL4757911)
Affinity DataIC50:  244nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340284(CHEMBL1760735 | N-(6-(2-(3-(2-(2-aminoethoxy)-5-(t...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340261(7-(2-(3-(2-fluoro-5-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340287(CHEMBL1760616 | N-methyl-7-(2-(3-(3-(trifluorometh...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553817(CHEMBL4740226)
Affinity DataIC50:  274nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340271(6-(2-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553824(CHEMBL4759319)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553824(CHEMBL4759319)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340278(CHEMBL1760638 | N-(6-(2-(3-(4-chloro-2-methoxy-5-m...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340267(7-(2-(3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-(t...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340268(6-(2-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureid...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340286(CHEMBL1760615 | N-methyl-7-(2-(3-(3-(trifluorometh...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553816(CHEMBL4784697)
Affinity DataIC50:  368nMAssay Description:Inhibition of ERK3 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50340289(CHEMBL1760618 | N-methyl-7-(2-(3-(4-(trifluorometh...)
Affinity DataIC50:  370nMAssay Description:Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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