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Found 110 with Last Name = 'burns' and Initial = 'jf'
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449332(CHEMBL3126041)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449331(CHEMBL3126043)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449330(CHEMBL3126045)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449329(CHEMBL3126046)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449328(CHEMBL3126047)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449327(CHEMBL3126039)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449326(CHEMBL3126040)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449325(CHEMBL3126044)
Affinity DataKi:  7nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449323(CHEMBL3126053)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449324(CHEMBL3126042)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449322(CHEMBL3126048)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449321(CHEMBL3126052)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449320(CHEMBL3126050)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449319(CHEMBL3126049)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141501(US8921370, 2 | US9656975, 2)
Affinity DataKi:  27nM ΔG°:  -43.2kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141501(US8921370, 2 | US9656975, 2)
Affinity DataKi:  27nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141506(US8921370, 160 | US9656975, 160)
Affinity DataKi:  35nM ΔG°:  -42.6kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141506(US8921370, 160 | US9656975, 160)
Affinity DataKi:  35nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141505(US8921370, 126 | US9656975, 126)
Affinity DataKi:  39nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141505(US8921370, 126 | US9656975, 126)
Affinity DataKi:  39nM ΔG°:  -42.3kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449318(CHEMBL3126051)
Affinity DataKi:  41nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141508(US8921370, 171 | US9656975, 171)
Affinity DataKi:  65nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141508(US8921370, 171 | US9656975, 171)
Affinity DataKi:  65nM ΔG°:  -41.0kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141502(US8921370, 6 | US9656975, 6)
Affinity DataKi:  78nM ΔG°:  -40.6kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141502(US8921370, 6 | US9656975, 6)
Affinity DataKi:  78nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141504(US8921370, 36 | US9656975, 36)
Affinity DataKi:  280nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141504(US8921370, 36 | US9656975, 36)
Affinity DataKi:  280nM ΔG°:  -37.4kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141503(US8921370, 15 | US9656975, 15)
Affinity DataKi:  340nM ΔG°:  -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141503(US8921370, 15 | US9656975, 15)
Affinity DataKi:  340nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141510(US8921370, 178 | US9656975, 178)
Affinity DataKi:  370nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141510(US8921370, 178 | US9656975, 178)
Affinity DataKi:  370nM ΔG°:  -36.7kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141509(US8921370, 176 | US9656975, 176)
Affinity DataKi:  500nM ΔG°:  -36.0kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141509(US8921370, 176 | US9656975, 176)
Affinity DataKi:  500nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449317(CHEMBL3126054)
Affinity DataKi:  720nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141507(US8921370, 161 | US9656975, 161)
Affinity DataKi:  1.20E+3nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141507(US8921370, 161 | US9656975, 161)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.8kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50449316(CHEMBL3126038)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141505(US8921370, 126 | US9656975, 126)
Affinity DataIC50:  0.320nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141505(US8921370, 126 | US9656975, 126)
Affinity DataIC50:  0.320nMpH: 7.4 T: 2°CAssay Description:The cDNA for rat metabotropic glutamate receptor 5 (rmGluR5) and the cDNA for human metabotropic glutamate receptor 5 (rmGluR5) were generous gifts f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141501(US8921370, 2 | US9656975, 2)
Affinity DataIC50:  3.70nMpH: 7.4 T: 2°CAssay Description:The cDNA for rat metabotropic glutamate receptor 5 (rmGluR5) and the cDNA for human metabotropic glutamate receptor 5 (rmGluR5) were generous gifts f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141501(US8921370, 2 | US9656975, 2)
Affinity DataIC50:  3.70nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141506(US8921370, 160 | US9656975, 160)
Affinity DataIC50:  3.90nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141506(US8921370, 160 | US9656975, 160)
Affinity DataIC50:  3.90nMpH: 7.4 T: 2°CAssay Description:The cDNA for rat metabotropic glutamate receptor 5 (rmGluR5) and the cDNA for human metabotropic glutamate receptor 5 (rmGluR5) were generous gifts f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141508(US8921370, 171 | US9656975, 171)
Affinity DataIC50:  4.70nMpH: 7.4 T: 2°CAssay Description:The cDNA for rat metabotropic glutamate receptor 5 (rmGluR5) and the cDNA for human metabotropic glutamate receptor 5 (rmGluR5) were generous gifts f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141508(US8921370, 171 | US9656975, 171)
Affinity DataIC50:  4.70nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141502(US8921370, 6 | US9656975, 6)
Affinity DataIC50:  9nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM141502(US8921370, 6 | US9656975, 6)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:The cDNA for rat metabotropic glutamate receptor 5 (rmGluR5) and the cDNA for human metabotropic glutamate receptor 5 (rmGluR5) were generous gifts f...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM50099566((2-fluorophenyl)-(4-fluorophenyl)phenylacetamide |...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50371390(CHEMBL272039)
Affinity DataIC50:  10nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50371391(SENICAPOC)
Affinity DataIC50:  12nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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