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Found 69 with Last Name = 'bush' and Initial = 'b'
TargetNeuromedin-K receptor(GUINEA PIG)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM85845(N-[(S)-1-Phenylpropyl]-2-phenyl-3-(carboxymethoxy)...)
Affinity DataKi:  1.60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM85845(N-[(S)-1-Phenylpropyl]-2-phenyl-3-(carboxymethoxy)...)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(mouse)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM85845(N-[(S)-1-Phenylpropyl]-2-phenyl-3-(carboxymethoxy)...)
Affinity DataKi:  17.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(mouse)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM85845(N-[(S)-1-Phenylpropyl]-2-phenyl-3-(carboxymethoxy)...)
Affinity DataKi:  82.4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Rattus norvegicus (Rat))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM85845(N-[(S)-1-Phenylpropyl]-2-phenyl-3-(carboxymethoxy)...)
Affinity DataKi:  2.33E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Rattus norvegicus (Rat))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM85845(N-[(S)-1-Phenylpropyl]-2-phenyl-3-(carboxymethoxy)...)
Affinity DataKi:  5.25E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(GUINEA PIG)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM85845(N-[(S)-1-Phenylpropyl]-2-phenyl-3-(carboxymethoxy)...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518185(CHEMBL4571977)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005321(5-[2-(2-Acetylamino-3-phenyl-propionylamino)-hexan...)
Affinity DataIC50:  0.840nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208999((R)-1-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of chemotaxis after 30 mins by Celltiter-glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50208999((R)-1-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-...)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056504(CHEMBL3334824)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of chemotaxis after 30 mins by Celltiter-glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518185(CHEMBL4571977)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of chemotaxis after 30 mins by Celltiter-glo reagent based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518184(CHEMBL4444976)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005318(CHEMBL166771 | {1-[1-(4-Butylcarbamoyl-1-cyclohexy...)
Affinity DataIC50:  2.10nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056504(CHEMBL3334824)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518184(CHEMBL4444976)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of chemotaxis after 30 mins by Celltiter-glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518200(CHEMBL4436061)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518188(CHEMBL4577357)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518186(CHEMBL4568048)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005312(5-[2-(3-Acetylamino-2-oxo-4-phenyl-piperidin-1-yl)...)
Affinity DataIC50:  21nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518164(CHEMBL4513370)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50398338(CHEMBL1628706)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of chemotaxis after 30 mins by Celltiter-glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518187(CHEMBL4583870)
Affinity DataIC50:  47nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50398338(CHEMBL1628706)
Affinity DataIC50:  59nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005319(6-Cyclohexyl-5-{2-[2-(1,3-dioxo-1,3-dihydro-isoind...)
Affinity DataIC50:  87nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005316(CHEMBL350357 | {1-[1-(4-Butylcarbamoyl-1-cyclohexy...)
Affinity DataIC50:  134nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005315(5-[2-(4-Acetylamino-3-oxo-1,3,4,5-tetrahydro-benzo...)
Affinity DataIC50:  210nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518173(CHEMBL4456839)
Affinity DataIC50:  350nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518201(CHEMBL4574870)
Affinity DataIC50:  420nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518163(CHEMBL4539264)
Affinity DataIC50:  500nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518182(CHEMBL4440166)
Affinity DataIC50:  600nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518183(CHEMBL4449368)
Affinity DataIC50:  790nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518197(CHEMBL4538794)
Affinity DataIC50:  960nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518176(CHEMBL4464403)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518163(CHEMBL4539264)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of chemotaxis after 30 mins by Celltiter-glo reagent based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518191(CHEMBL4565390)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005313(CHEMBL169718 | {2-[1-(4-Butylcarbamoyl-1-cyclohexy...)
Affinity DataIC50:  1.73E+3nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518166(CHEMBL4468514)
Affinity DataIC50:  1.90E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005317(5-[2-(4-Amino-3-oxo-1,3,4,5-tetrahydro-benzo[c]aze...)
Affinity DataIC50:  2.04E+3nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518193(CHEMBL4571547)
Affinity DataIC50:  2.10E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518195(CHEMBL4462565)
Affinity DataIC50:  2.40E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518199(CHEMBL4452387)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518198(CHEMBL4436168)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518196(CHEMBL4548382)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518194(CHEMBL4462862)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518192(CHEMBL4579581)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518190(CHEMBL4589222)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518189(CHEMBL4515118)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50518181(CHEMBL4469919)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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