Compile Data Set for Download or QSAR
maximum 50k data
Found 31 with Last Name = 'busonera' and Initial = 'b'
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  14nMAssay Description:Inhibitory concentration against HIV-1 wild type reverse transcriptase (IIIB)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (Y181C)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50168052((4-Iodo-phenyl)-thiocarbamic acid 2-(1,3-dioxo-1,3...)
Affinity DataIC50:  90nMAssay Description:Inhibitory concentration against HIV-1 wild type reverse transcriptase (IIIB)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103N+Y181C)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50168128(CHEMBL191655 | O-2-(1,3-dioxoisoindolin-2-yl)ethyl...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration against HIV-1 virion reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM1866(3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]t...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibitory concentration against HIV-1 wild type reverse transcriptase (IIIB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50168060(CHEMBL195108 | N-[2-(4-Iodo-phenylthiocarbamoyloxy...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory concentration against HIV-1 wild type reverse transcriptase (IIIB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493837(CHEMBL2443298)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493837(CHEMBL2443298)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103R)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50168052((4-Iodo-phenyl)-thiocarbamic acid 2-(1,3-dioxo-1,3...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103R)More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493838(CHEMBL2443297)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493846(CHEMBL2443290)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493835(CHEMBL2443288)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50168060(CHEMBL195108 | N-[2-(4-Iodo-phenylthiocarbamoyloxy...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (Y181C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM1866(3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]t...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (Y181C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM1866(3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]t...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50168052((4-Iodo-phenyl)-thiocarbamic acid 2-(1,3-dioxo-1,3...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103N+Y181C)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50168060(CHEMBL195108 | N-[2-(4-Iodo-phenylthiocarbamoyloxy...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50168052((4-Iodo-phenyl)-thiocarbamic acid 2-(1,3-dioxo-1,3...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (Y181C)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM1866(3-(5-bromopyridin-2-yl)-1-[2-(pyridin-2-yl)ethyl]t...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103N+Y181C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Universit£

Curated by ChEMBL
LigandPNGBDBM50168060(CHEMBL195108 | N-[2-(4-Iodo-phenylthiocarbamoyloxy...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103N+Y181C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM241949(US9428466, Merbarone)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493842(CHEMBL2443291)
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493841(CHEMBL2443289)
Affinity DataIC50: >3.50E+4nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493845(CHEMBL2443300)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493844(CHEMBL2440361)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493843(CHEMBL2443296)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493839(CHEMBL2443292)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493836(CHEMBL2443299)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50493840(CHEMBL2440360)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed