BindingDB PrimarySearch

Found 79 with Last Name = 'bye' and Initial = 'r'

Alpha-glucosidase MAL62(Saccharomyces cerevisiae)
Universidad Nacional Auto£?Noma De Me£?Xico

Curated by ChEMBL

BDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)

Ki: 4.60E+5nMAssay Description:Inhibition of yeast alpha-glucosidase assessed as inhibition of p-nitrophenyl-alpha-D-glucopyranoside substrate hydrolysis after 35 mins by spectrosc...More data for this Ligand-Target Pair

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Alpha-glucosidase MAL62(Saccharomyces cerevisiae)
Universidad Nacional Auto£?Noma De Me£?Xico

Curated by ChEMBL

BDBM50341204((Z)-3-butylidenephthalide | CHEMBL1765390)

Ki: 4.86E+6nMAssay Description:Inhibition of yeast alpha-glucosidase assessed as inhibition of p-nitrophenyl-alpha-D-glucopyranoside substrate hydrolysis after 35 mins by spectrosc...More data for this Ligand-Target Pair

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Glutamate carboxypeptidase 2(Homo sapiens (Human))
Washington State University

Curated by ChEMBL

BDBM50358646(CHEMBL1921899)

IC50: 0.350nMAssay Description:Inhibition of PSMA using N-[4-(phenylazo)-benzoyl]-glutamyl-gamma-glutamic acid as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair

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Glutamate carboxypeptidase 2(Homo sapiens (Human))
Washington State University

Curated by ChEMBL

BDBM50358645(CHEMBL1921898)

IC50: 0.410nMAssay Description:Inhibition of PSMA using N-[4-(phenylazo)-benzoyl]-glutamyl-gamma-glutamic acid as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair

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Glutamate carboxypeptidase 2(Homo sapiens (Human))
Washington State University

Curated by ChEMBL

BDBM50358647(CHEMBL1921900)

IC50: 1.93nMAssay Description:Inhibition of PSMA using N-[4-(phenylazo)-benzoyl]-glutamyl-gamma-glutamic acid as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair

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Glutamate carboxypeptidase 2(Homo sapiens (Human))
Washington State University

Curated by ChEMBL

BDBM50358644(CHEMBL1921897)

IC50: 14nMAssay Description:Inhibition of PSMA using N-[4-(phenylazo)-benzoyl]-glutamyl-gamma-glutamic acid as substrate after 15 mins by HPLC analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477454(CHEMBL245688)

IC50: 100nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477429(CHEMBL248132)

IC50: 300nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477447(CHEMBL248327)

IC50: 500nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477441(CHEMBL247674)

IC50: 500nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477437(CHEMBL247930)

IC50: 600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477456(CHEMBL392878)

IC50: 600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50105462(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)

IC50: 600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477434(CHEMBL247931)

IC50: 600nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477428(CHEMBL248131)

IC50: 700nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477439(CHEMBL247524)

IC50: 700nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)

IC50: 800nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477435(CHEMBL247328)

IC50: 800nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477426(CHEMBL391205)

IC50: 800nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477450(CHEMBL247725)

IC50: 900nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477446(CHEMBL394713)

IC50: 900nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477444(CHEMBL247927)

IC50: 900nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477448(CHEMBL247932)

IC50: 1.00E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477448(CHEMBL247932)

IC50: 1.00E+3nMAssay Description:Inhibition of amyloid beta fibril aggregation (unknown origin) by thioflavin T fluorescence methodMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477438(CHEMBL248122)

IC50: 1.10E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477436(CHEMBL247530)

IC50: 1.10E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477455(CHEMBL247929)

IC50: 1.10E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477431(CHEMBL427878)

IC50: 1.10E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477453(CHEMBL248337)

IC50: 1.10E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477433(CHEMBL248133)

IC50: 1.30E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477451(CHEMBL247727)

IC50: 1.40E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477445(CHEMBL247726)

IC50: 1.70E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477452(CHEMBL396917)

IC50: 1.80E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477432(CHEMBL247728)

IC50: 1.90E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477443(CHEMBL427877)

IC50: 2.30E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477425(CHEMBL248338)

IC50: 2.70E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50204084(5-((E)-2-{4-[(E)-2-(3-carboxy-4-hydroxyphenyl)viny...)

IC50: 8.00E+3nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477442(CHEMBL245476)

IC50: 2.00E+4nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477449(CHEMBL248339)

IC50: >2.00E+4nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477440(CHEMBL245478)

IC50: >2.00E+4nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477430(CHEMBL245477)

IC50: >2.00E+4nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Amyloid-beta precursor protein(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL

BDBM50477427(CHEMBL245479)

IC50: >2.00E+4nMAssay Description:Inhibition of amyloid beta 42 fibril formation by thioflavin T assayMore data for this Ligand-Target Pair

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Alpha-xylosidase(Blautia obeum)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL

BDBM50412283(CHEMBL476314)

IC50: 6.00E+4nMAssay Description:Inhibition of recombinant Ruminococcus obeum ATCC 29174 alpha-glucosidase expressed in Escherichia coli BL21(DE3) using p-nitrophenyl-alpha-D-glucopy...More data for this Ligand-Target Pair

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Alpha-xylosidase(Blautia obeum)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL

BDBM50270473(CHEMBL4127208)

IC50: 4.00E+5nMAssay Description:Inhibition of recombinant Ruminococcus obeum ATCC 29174 alpha-glucosidase expressed in Escherichia coli BL21(DE3) using p-nitrophenyl-alpha-D-glucopy...More data for this Ligand-Target Pair

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Alpha-glucosidase MAL62(Saccharomyces cerevisiae)
Universidad Nacional Auto£?Noma De Me£?Xico

Curated by ChEMBL

BDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)

IC50: 4.20E+5nMAssay Description:Inhibition of yeast alpha-glucosidase assessed as inhibition of p-nitrophenyl-alpha-D-glucopyranoside substrate hydrolysis after 35 mins by spectrosc...More data for this Ligand-Target Pair

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Alpha-xylosidase(Blautia obeum)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL

BDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)

IC50: 1.03E+6nMAssay Description:Inhibition of recombinant Ruminococcus obeum ATCC 29174 alpha-glucosidase expressed in Escherichia coli BL21(DE3) using p-nitrophenyl-alpha-D-glucopy...More data for this Ligand-Target Pair

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Alpha-glucosidase MAL62(Saccharomyces cerevisiae)
Universidad Nacional Auto£?Noma De Me£?Xico

Curated by ChEMBL

BDBM50341204((Z)-3-butylidenephthalide | CHEMBL1765390)

IC50: 2.35E+6nMAssay Description:Inhibition of yeast alpha-glucosidase assessed as inhibition of p-nitrophenyl-alpha-D-glucopyranoside substrate hydrolysis after 35 mins by spectrosc...More data for this Ligand-Target Pair

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Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL

BDBM50504656(CHEMBL1549549)

EC50: 1.46E+3nMAssay Description:Activation of NRF2 in human U2OS cells co-expressing Keap1 (unknown origin) assessed as induction of NRF2 translocation to nucleus incubated for 6 hr...More data for this Ligand-Target Pair

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Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL

BDBM50504657(CHEMBL4577531)

EC50: 2.30E+3nMAssay Description:Activation of NRF2 in human U2OS cells co-expressing Keap1 (unknown origin) assessed as induction of NRF2 translocation to nucleus incubated for 6 hr...More data for this Ligand-Target Pair

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Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL

BDBM50504658(CHEMBL4564810)

EC50: 2.84E+3nMAssay Description:Activation of NRF2 in human U2OS cells co-expressing Keap1 (unknown origin) assessed as induction of NRF2 translocation to nucleus incubated for 6 hr...More data for this Ligand-Target Pair

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Displayed 1 to 50 (of 79 total ) | Next | Last >>

Filter my 79 hits

Targets 5▿
- Amyloid-beta precursor protein 36
- Nuclear factor erythroid 2-related factor 2 32
- Glutamate carboxypeptidase 2 4
- Alpha-glucosidase MAL62 4
- Alpha-xylosidase 3
Publications 6▿
- Bioorg Med Chem Lett 17: 1466-70 (2007) 35
- Eur J Med Chem 185: (2020) 32
- J Nat Prod 74: 314-20 (2011) 4
- Bioorg Med Chem Lett 21: 7013-6 (2011) 4
- J Nat Prod 80: 1584-1593 (2017) 3
- Bioorg Med Chem Lett 23: 3467-9 (2013) 1
Institutions 5▿
- Korea Institute Of Science And Technology 36
- Korea Institute Of Science And Technology (Kist) 32
- Universidad Nacional Auto£?Noma De Me£?Xico 4
- Washington State University 4
- Universidad Nacional Aut£Noma De M£Xico 3
Affinity: 0.35 to 4.9E+6 nM▿
- Ki 2
- IC50 45
- EC50 32
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 9