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Found 34 with Last Name = 'bzdega' and Initial = 't'
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143073((S)-2-{3-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propy...)
Affinity DataKi:  0.900nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM17659((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...)
Affinity DataKi:  1.40nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143074((S)-2-[3-((S)-Carboxy-phenyl-methyl)-ureido]-penta...)
Affinity DataKi:  2.10nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143078((S)-2-{3-[(S)-1-Carboxy-2-(4-hydroxy-phenyl)-ethyl...)
Affinity DataKi:  3nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143070((S)-2-(3-{(S)-1-Carboxy-3-[1-(2-cyano-ethyl)-1H-te...)
Affinity DataKi:  5.30nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143080((S)-2-{3-[(S)-Carboxy-(4-hydroxy-phenyl)-methyl]-u...)
Affinity DataKi:  5.90nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50102258((S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-ureido]-...)
Affinity DataKi:  8nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143069((S)-2-[3-((S)-1-Carboxy-2-phenyl-ethyl)-ureido]-pe...)
Affinity DataKi:  12nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143066((2S,5S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-urei...)
Affinity DataKi:  14.4nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143068((S)-2-{3-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propy...)
Affinity DataKi:  14.9nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143064((2S,5R)-2-Benzyl-4-[3-((S)-3-carboxy-1-carboxy-pro...)
Affinity DataKi:  95.3nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143077((S)-2-{3-[(S)-3-Carboxy-1-(1H-tetrazol-5-yl)-propy...)
Affinity DataKi:  335nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143075((2S,5R)-2-[3-((S)-3-Carboxy-1-carboxy-4-phenyl-but...)
Affinity DataKi:  392nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143072((S)-2-[3-((S)-1,3-Dicarboxy-1-methyl-propyl)-ureid...)
Affinity DataKi:  939nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398813(CHEMBL2114987)
Affinity DataKi:  1.11E+3nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398814(CHEMBL2115435)
Affinity DataKi:  1.29E+3nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143067((S)-2-(3-{(S)-3-Carboxy-1-[1-(2-cyano-ethyl)-1H-te...)
Affinity DataKi:  2.71E+3nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143065((S)-4-{3-[(S)-3-Carboxy-1-(1H-tetrazol-5-yl)-propy...)
Affinity DataKi:  4.39E+3nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143079((S)-2-(3-{(S)-1-Carboxy-3-[1-(2-cyano-ethyl)-1H-te...)
Affinity DataKi:  4.43E+3nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acetylated-alpha-linked acidic dipeptidase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50143071((S)-4-(3-{(S)-3-Carboxy-1-[1-(2-cyano-ethyl)-1H-te...)
Affinity DataKi: >1.00E+5nMAssay Description:In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM17659((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...)
Affinity DataIC50:  5.10nMAssay Description:Inhibitory activity of the compound against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 microMMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50102256(2-[3-(1-Carboxy-2-mercapto-ethyl)-ureido]-pentaned...)
Affinity DataIC50:  6.90nMAssay Description:Inhibitory activity of the compound against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50102259(2-[(2,4-Dicarboxy-butyl)-hydroxy-phosphinoylmethyl...)
Affinity DataIC50:  21.7nMAssay Description:Inhibitory activity of the compound against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50102255(2-[3-(2-tert-Butylsulfanyl-1-carboxy-ethyl)-ureido...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity of the compound against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50102257(2-[3-(1,2-Dicarboxy-ethyl)-ureido]-pentanedioic ac...)
Affinity DataIC50:  46.1nMAssay Description:Inhibitory activity of the compound against expressed rat Glutamate carboxypeptidase IIusing a substrate concentration of 5 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50102258((S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-ureido]-...)
Affinity DataIC50:  47nMAssay Description:Inhibitory activity of the compound against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50102260(2-(2-Amino-4-carboxy-butyrylamino)-pentanedioic ac...)
Affinity DataIC50:  750nMAssay Description:Inhibitory activity of the compound against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50102262(2-(2-Amino-3-carboxy-propionylamino)-pentanedioic ...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity of the compound against expressed rat Glutamate carboxypeptidase IIusing a substrate concentration of 5 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50102261(2-[3-(1,2-Dicarboxy-ethyl)-ureido]-succinic acid |...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibitory activity of the compound against expressed rat Glutamate carboxypeptidase IIusing a substrate concentration of 5 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085699((S,S / R,R)4-Carboxy-5-[(2,4-dicarboxy-butyl)-hydr...)
Affinity DataEC50:  4.50E+4nMAssay Description:Agonist potency of the compound against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085699((S,S / R,R)4-Carboxy-5-[(2,4-dicarboxy-butyl)-hydr...)
Affinity DataEC50:  3.90E+4nMAssay Description:Agonist potency of the compound against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085699((S,S / R,R)4-Carboxy-5-[(2,4-dicarboxy-butyl)-hydr...)
Affinity DataEC50:  3.90E+4nMAssay Description:Agonist potency of the compound against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085700((R,R / S,S) 4-Carboxy-5-[(2,4-dicarboxy-butyl)-hyd...)
Affinity DataEC50:  3.30E+4nMAssay Description:Agonist potency of the compound against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085701(4,8-Dicarboxy-6-oxo-undecanedioic acid | CHEMBL164...)
Affinity DataEC50: >3.00E+5nMAssay Description:Agonist potency of the compound against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed