Affinity DataKi: 400nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human HEK cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of MCP1-induced CCR2-mediated chemotaxis in human THP-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against delta receptor of (endomorphin 2) in mouse vas deferens was determinedMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Roche Discover Welwyn
Curated by ChEMBL
Roche Discover Welwyn
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human CCR5 by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair