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Found 75 with Last Name = 'carpenter' and Initial = 'sh'
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054502(CHEMBL140494 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataKi:  1.01nMAssay Description:compound was tested in vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  0.467nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  0.505nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50:  0.700nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054493(CHEMBL343805 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  0.710nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054492((S)-4-[(R)-2-((S)-3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  1.10nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054494(2-({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohex...)
Affinity DataIC50:  1.12nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054492((S)-4-[(R)-2-((S)-3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  1.36nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50:  1.52nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054502(CHEMBL140494 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  6.20nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  6.20nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054504(2-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl)-N...)
Affinity DataIC50:  14.2nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054504(2-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl)-N...)
Affinity DataIC50:  16.6nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054493(CHEMBL343805 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  20.6nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50076074(1N-[1-amino(imino)methyl-6-hydroxy-(5S)-tetrahydro...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054493(CHEMBL343805 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  74.5nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054503(CHEMBL263924 | N-((1S,2R)-3-Carbamimidoyl-2-hydrox...)
Affinity DataIC50:  111nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054505(CHEMBL421760 | N-(3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  125nMAssay Description:compound was tested in vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054494(2-({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohex...)
Affinity DataIC50:  137nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  141nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054495(CHEMBL422470 | Lactum Sulfonamide analogue)
Affinity DataIC50:  147nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054489(CHEMBL139656 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  157nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054491(2-((S)-3-Benzenesulfonylamino-2-oxo-piperidin-1-yl...)
Affinity DataIC50:  159nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  160nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054495(CHEMBL422470 | Lactum Sulfonamide analogue)
Affinity DataIC50:  235nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054499(CHEMBL334454 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  286nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054492((S)-4-[(R)-2-((S)-3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  290nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054499(CHEMBL334454 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  293nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  396nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054490(CHEMBL138243 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  420nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289560(CHEMBL289389 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  447nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054489(CHEMBL139656 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  467nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054494(2-({(S)-1-[((S)-3-Carbamimidoyl-2-hydroxy-cyclohex...)
Affinity DataIC50:  471nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054504(2-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl)-N...)
Affinity DataIC50:  479nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054505(CHEMBL421760 | N-(3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  538nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50:  709nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054491(2-((S)-3-Benzenesulfonylamino-2-oxo-piperidin-1-yl...)
Affinity DataIC50:  770nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054502(CHEMBL140494 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)
Affinity DataIC50:  791nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50:  791nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50289559(CHEMBL39475 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  905nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054503(CHEMBL263924 | N-((1S,2R)-3-Carbamimidoyl-2-hydrox...)
Affinity DataIC50:  1.02E+3nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054491(2-((S)-3-Benzenesulfonylamino-2-oxo-piperidin-1-yl...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054500(CHEMBL140646 | {(S)-1-[((S)-3-Carbamimidoyl-2-hydr...)
Affinity DataIC50:  1.46E+3nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054495(CHEMBL422470 | Lactum Sulfonamide analogue)
Affinity DataIC50:  1.95E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50:  2.50E+3nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054498((R)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
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