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Found 73 with Last Name = 'carver' and Initial = 'te'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162972(4-(Benzothiazol-6-ylamino)-6-(benzyl-isopropyl-ami...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162976(4-(Benzothiazol-6-ylamino)-6-(1-methyl-1-phenyl-et...)
Affinity DataIC50:  35nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162978(4-(Benzothiazol-6-ylamino)-6-(benzyl-ethyl-amino)-...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162972(4-(Benzothiazol-6-ylamino)-6-(benzyl-isopropyl-ami...)
Affinity DataIC50:  180nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162975(4-(3H-Benzoimidazol-5-ylamino)-6-(1-methyl-1-pheny...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162972(4-(Benzothiazol-6-ylamino)-6-(benzyl-isopropyl-ami...)
Affinity DataIC50:  280nMAssay Description:Inhibition of KDR-induced MAP kinase autophosphorylation assay in HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162974(4-(Benzothiazol-5-ylamino)-6-(benzyl-methyl-amino)...)
Affinity DataIC50:  320nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162974(4-(Benzothiazol-5-ylamino)-6-(benzyl-methyl-amino)...)
Affinity DataIC50:  320nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162976(4-(Benzothiazol-6-ylamino)-6-(1-methyl-1-phenyl-et...)
Affinity DataIC50:  400nMAssay Description:Inhibition of KDR-induced MAP kinase autophosphorylation assay in HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162978(4-(Benzothiazol-6-ylamino)-6-(benzyl-ethyl-amino)-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Affinity DataIC50:  420nMAssay Description:Inhibition of beta IRK tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31285(BMCL163310 Compound 1 | CHEMBL361103 | benzodiazep...)
Affinity DataIC50:  420nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31328(1,4-benzodiazepine-2,5-dione antagonist, 13 | Race...)
Affinity DataIC50:  510nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31318(1,4-benzodiazepine-2,5-dione antagonist, 2 | Racem...)
Affinity DataIC50:  540nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162976(4-(Benzothiazol-6-ylamino)-6-(1-methyl-1-phenyl-et...)
Affinity DataIC50:  550nMAssay Description:Inhibition of beta IRK tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162978(4-(Benzothiazol-6-ylamino)-6-(benzyl-ethyl-amino)-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of KDR-induced MAP kinase autophosphorylation assay in HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Affinity DataIC50:  700nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31305(1,4-benzodiazepine-2,5-dione, 12b | BMCL163310 Com...)
Affinity DataIC50:  700nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31338(1,4-benzodiazepine-2,5-dione antagonist, 23)
Affinity DataIC50:  710nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31320(1,4-benzodiazepine-2,5-dione antagonist, 4 | Racem...)
Affinity DataIC50:  850nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31321(1,4-benzodiazepine-2,5-dione antagonist, 5 | Racem...)
Affinity DataIC50:  870nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31336(1,4-benzodiazepine-2,5-dione antagonist, 21)
Affinity DataIC50:  980nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162976(4-(Benzothiazol-6-ylamino)-6-(1-methyl-1-phenyl-et...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31337(1,4-benzodiazepine-2,5-dione antagonist, 22)
Affinity DataIC50:  1.04E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31327(1,4-benzodiazepine-2,5-dione antagonist, 12 | Race...)
Affinity DataIC50:  1.09E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31339(1,4-benzodiazepine-2,5-dione antagonist, 24)
Affinity DataIC50:  1.11E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162977(4-(Benzothiazol-6-yl-methyl-amino)-6-(1-methyl-1-p...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162981(4-(Benzothiazol-6-ylamino)-6-benzylamino-[1,3,5]tr...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31319(1,4-benzodiazepine-2,5-dione antagonist, 3 | Racem...)
Affinity DataIC50:  2.12E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31331(1,4-benzodiazepine-2,5-dione antagonist, 16 | Race...)
Affinity DataIC50:  2.13E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31335(1,4-benzodiazepine-2,5-dione antagonist, 20 | Race...)
Affinity DataIC50:  2.15E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31323(1,4-benzodiazepine-2,5-dione antagonist, 8 | Racem...)
Affinity DataIC50:  2.18E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162978(4-(Benzothiazol-6-ylamino)-6-(benzyl-ethyl-amino)-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of PDGF-R2 tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31330(1,4-benzodiazepine-2,5-dione antagonist, 15 | Race...)
Affinity DataIC50:  2.82E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31324(1,4-benzodiazepine-2,5-dione antagonist, 9 | Racem...)
Affinity DataIC50:  3.33E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of PDGF-R2 tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162978(4-(Benzothiazol-6-ylamino)-6-(benzyl-ethyl-amino)-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of beta IRK tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162978(4-(Benzothiazol-6-ylamino)-6-(benzyl-ethyl-amino)-...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of c-fms tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31325(1,4-benzodiazepine-2,5-dione antagonist, 10 | Race...)
Affinity DataIC50:  4.35E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162980(CHEMBL175760 | N-Benzothiazol-6-yl-6-chloro-N''-(1...)
Affinity DataIC50:  5.50E+3nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162980(CHEMBL175760 | N-Benzothiazol-6-yl-6-chloro-N''-(1...)
Affinity DataIC50:  5.50E+3nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162979(CHEMBL175506 | N-Benzothiazol-6-yl-6-methoxy-N''-(...)
Affinity DataIC50:  6.10E+3nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162976(4-(Benzothiazol-6-ylamino)-6-(1-methyl-1-phenyl-et...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of PDGF-R2 tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31332(1,4-benzodiazepine-2,5-dione antagonist, 17 | Race...)
Affinity DataIC50:  8.22E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162977(4-(Benzothiazol-6-yl-methyl-amino)-6-(1-methyl-1-p...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of KDR-induced MAP kinase autophosphorylation assay in HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Mus musculus)
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse Fibroblast growth factor receptor 1 expressed in NIH 3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Mus musculus)
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162978(4-(Benzothiazol-6-ylamino)-6-(benzyl-ethyl-amino)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse Fibroblast growth factor receptor 1 expressed in NIH 3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162973(CHEMBL177298 | N-[4-(Benzothiazol-6-ylamino)-6-(1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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