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Found 82 with Last Name = 'caselli' and Initial = 'a'
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50367249(CHEMBL309601)
Affinity DataKi:  0.5nMAssay Description:Compound was evaluated for the inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020843(2-[(2S)-2-carboxypyrrolidin-1-yl]-1-methyl-2-oxoet...)
Affinity DataKi:  1.40nMAssay Description:Compound was evaluated for the inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444695(CHEMBL3098852)
Affinity DataKi:  500nMAssay Description:Mixed type inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Double reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444693(CHEMBL3098944)
Affinity DataKi:  1.40E+3nMAssay Description:Noncompetitive inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Double reciprocal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444694(CHEMBL3098854)
Affinity DataKi:  1.50E+3nMAssay Description:Mixed type inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Double reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444692(CHEMBL3098853)
Affinity DataKi:  1.50E+3nMAssay Description:Competitive inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Double reciprocal pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444696(CHEMBL3098942)
Affinity DataKi:  2.30E+3nMAssay Description:Mixed type inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Double reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of marmoset plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of Human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  2nMpH: 7.2Assay Description:In vitro inhibition of porcine plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  2nMpH: 7.2Assay Description:In vitro inhibition of marmoset plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022586(5-[2-[2-Benzyl-3-(2-methyl-propane-2-sulfinyl)-pro...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022587(5-[2-(2-tert-Butylsulfanylmethyl-3-phenyl-propiony...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022588(CHEMBL291787 | {2-[1-(4-Butylcarbamoyl-1-cyclohexy...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022584(2-Benzyl-5,5-dimethyl-4-oxo-hexanoic acid [1-(4-bu...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022590(2,2-Dimethyl-propionic acid 1-[1-(4-butylcarbamoyl...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022859(CHEMBL407670 | Pro-His-Pro-Phe-His-Leu[CH2NH]Val-I...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022589(CHEMBL435178 | {1-[1-(4-{1-[1-Carbamoyl-2-(3H-imid...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022585(5-[2-[2-(2,2-Dimethyl-propionylamino)-3-phenyl-pro...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022591(2,2-Dimethyl-propionic acid 1-[1-(4-{1-[1-carbamoy...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022581(2,2-Dimethyl-propionic acid 1-[1-(4-butylcarbamoyl...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of rat plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444695(CHEMBL3098852)
Affinity DataIC50:  700nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444697(CHEMBL3098857)
Affinity DataIC50:  800nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444693(CHEMBL3098944)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444695(CHEMBL3098852)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444698(CHEMBL3098856)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444692(CHEMBL3098853)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444700(CHEMBL3098851)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444697(CHEMBL3098857)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444696(CHEMBL3098942)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444694(CHEMBL3098854)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  3.20E+3nMAssay Description:In vitro inhibition of bovine cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444697(CHEMBL3098857)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human recombinant LMW-PTP IF1 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444694(CHEMBL3098854)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444702(CHEMBL3098946)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444693(CHEMBL3098944)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444699(CHEMBL3098855)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444703(CHEMBL3098945)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444695(CHEMBL3098852)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant LMW-PTP IF1 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444699(CHEMBL3098855)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444692(CHEMBL3098853)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444698(CHEMBL3098856)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant LMW-PTP IF1 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444700(CHEMBL3098851)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444702(CHEMBL3098946)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444698(CHEMBL3098856)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444696(CHEMBL3098942)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444705(CHEMBL3098941)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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