BindingDB PrimarySearch

Found 250 with Last Name = 'catinella' and Initial = 's'

Beta-2 adrenergic receptor(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

Ki: 0.00398nMAssay Description:Displacement of 125I-cyanopindolol from human beta2 adrenoceptor expressed in CHO-K1 cell membrane measured after 1 hr by Cheng-prusoff equation anal...More data for this Ligand-Target Pair

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Beta-2 adrenergic receptor(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595404(CHEMBL5184455)

Ki: 0.0200nMAssay Description:Displacement of 125I-cyanopindolol from human beta2 adrenoceptor expressed in CHO-K1 cell membrane measured after 1 hr by Cheng-prusoff equation anal...More data for this Ligand-Target Pair

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Beta-2 adrenergic receptor(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595426(CHEMBL5193853)

Ki: 0.0251nMAssay Description:Displacement of 125I-cyanopindolol from human beta2 adrenoceptor expressed in CHO-K1 cell membrane measured after 1 hr by Cheng-prusoff equation anal...More data for this Ligand-Target Pair

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Beta-2 adrenergic receptor(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595423(CHEMBL5190387)

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Beta-2 adrenergic receptor(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595427(CHEMBL5200887)

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Beta-2 adrenergic receptor(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595403(CHEMBL5208201)

Ki: 0.0398nMAssay Description:Displacement of 125I-cyanopindolol from human beta2 adrenoceptor expressed in CHO-K1 cell membrane measured after 1 hr by Cheng-prusoff equation anal...More data for this Ligand-Target Pair

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Beta-2 adrenergic receptor(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595425(CHEMBL5208957)

Ki: 0.0501nMAssay Description:Displacement of 125I-cyanopindolol from human beta2 adrenoceptor expressed in CHO-K1 cell membrane measured after 1 hr by Cheng-prusoff equation anal...More data for this Ligand-Target Pair

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Beta-2 adrenergic receptor(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595405(CHEMBL5184598)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595424(CHEMBL5172865)

Ki: 0.0631nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595423(CHEMBL5190387)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595426(CHEMBL5193853)

Ki: 0.0794nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50569301(CHEMBL4854091)

Ki: 0.126nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595404(CHEMBL5184455)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595425(CHEMBL5208957)

Ki: 0.158nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595427(CHEMBL5200887)

Ki: 0.200nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Beta-2 adrenergic receptor(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50569301(CHEMBL4854091)

Ki: 0.251nMAssay Description:Displacement of 125I-cyanopindolol from human beta2 adrenoceptor expressed in CHO-K1 cell membrane measured after 1 hr by Cheng-prusoff equation anal...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595403(CHEMBL5208201)

Ki: 0.316nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595405(CHEMBL5184598)

Ki: 0.794nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595406(CHEMBL5200448)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595422(CHEMBL5177499)

Ki: 1nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595408(CHEMBL5195203)

Ki: 1.60nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595418(CHEMBL5179380)

Ki: 3.20nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595416(CHEMBL5178217)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595414(CHEMBL5187593)

Ki: 4nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595419(CHEMBL5194569)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595420(CHEMBL5193776)

Ki: 5nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595415(CHEMBL5202045)

Ki: 6.30nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595410(CHEMBL5202787)

Ki: 7.90nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595413(CHEMBL5195224)

PDB Reactome pathway KEGG
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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595412(CHEMBL5181855)

PDB Reactome pathway KEGG
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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595409(CHEMBL5202567)

PDB Reactome pathway KEGG
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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595417(CHEMBL5207792)

Ki: 10nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595411(CHEMBL5170720)

Ki: 25nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Beta-2 adrenergic receptor(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595429(CHEMBL5201712)

Ki: 25nMAssay Description:Displacement of 125I-cyanopindolol from human beta2 adrenoceptor expressed in CHO-K1 cell membrane measured after 1 hr by Cheng-prusoff equation anal...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595407(CHEMBL5193865)

PDB Reactome pathway KEGG
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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595428(CHEMBL5203937)

Ki: 40nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50595421(CHEMBL5180420)

Ki: 200nMAssay Description:Displacement of [3H]-methylscopolamine from human muscarinic M3 receptor expressed in CHO-K1 cell membrane measured after 2 hr by Cheng-prusoff equat...More data for this Ligand-Target Pair

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cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50246909(CHEMBL4075951)

IC50: 0.0280nMAssay Description:Inhibition of human recombinant PDE4B expressed insect sf9 cells by radiometric assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495750(CHEMBL3113949)

IC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495735(CHEMBL3113954)

IC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495736(CHEMBL3113948)

IC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495709(CHEMBL3113966)

IC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495704(Chf-6001 | Chf6001 | J3.309.618F)

IC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495703(CHEMBL3113943)

IC50: 0.0400nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495710(CHEMBL3113976)

IC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495733(CHEMBL3113962)

IC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495747(CHEMBL3113968)

IC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495725(CHEMBL3113946)

IC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495746(CHEMBL3113953)

IC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50495703(CHEMBL3113943)

IC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Displayed 1 to 50 (of 250 total ) | Next | Last >>

Filter my 250 hits

Targets 26▿
- cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D 98
- Amyloid-beta precursor protein 33
- Muscarinic acetylcholine receptor M3 27
- Beta-2 adrenergic receptor 18
- Cytochrome P450 2C9 9
- Cytochrome P450 2C19 8
- Cytochrome P450 3A4 8
- Muscarinic acetylcholine receptor 8
- cGMP-specific 3',5'-cyclic phosphodiesterase 3
- Prostaglandin G/H synthase 1 3
- cGMP-dependent 3',5'-cyclic phosphodiesterase 3
- Voltage-dependent L-type calcium channel subunit alpha-1C 3
- Cytochrome P450 2D6 3
- Potassium voltage-gated channel subfamily H member 2 3
- Sodium channel protein type 5 subunit alpha 3
- High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 2
- Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 2
- Prostaglandin G/H synthase 2 2
- cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A 2
- High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A 2
- Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 2
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B 2
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2
- High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 2
- Cytochrome P450 1A2 1
- cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B 1
- ...
Publications 4▿
- J Med Chem 57: 793-816 (2014) 101
- J Med Chem 48: 5705-20 (2005) 67
- J Med Chem 65: 10233-10250 (2022) 62
- J Med Chem 60: 10026-10046 (2017) 20
Institutions 1▿
- Chiesi Farmaceutici 250
Affinity: 0.0040 to 4.1E+5 nM▿
- Ki 37
- IC50 213
- Affinity ≤ nM
Xtal structures: 3
Docked structures: 0
Catalog Cmpds: 7