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Found 66 with Last Name = 'celen' and Initial = 's'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50401389(CHEMBL2206441)
Affinity DataKi:  5.01E+3nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50401387(CHEMBL2206445)
Affinity DataKi: >8.50E+3nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Homo sapiens (Human))
Katholieke Universiteit Leuven

Curated by ChEMBL
LigandPNGBDBM50298560(1-(beta-D-galactopyranosyl)-4-phenyl-1,2,3-triazol...)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of beta-galactosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM31592(PF-2545920 | US9138494, MP-10 | substituted pyraz...)
Affinity DataIC50:  0.501nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419436(CHEMBL1915747 | US9138494, JNJ-41510417)
Affinity DataIC50:  0.501nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50357701(CHEMBL1915725 | US9138494, Janssen B-3)
Affinity DataIC50:  1.58nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419439(CHEMBL1915727)
Affinity DataIC50:  2.51nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419437(CHEMBL1915742)
Affinity DataIC50:  3.16nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50357702(CHEMBL1915726)
Affinity DataIC50:  3.16nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419442(CHEMBL1915746)
Affinity DataIC50:  3.98nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419428(CHEMBL1915736)
Affinity DataIC50:  3.98nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419423(CHEMBL1915729)
Affinity DataIC50:  5.01nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419426(CHEMBL1915733)
Affinity DataIC50:  5.01nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50401385(CHEMBL2206447)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50401386(CHEMBL2206446)
Affinity DataIC50:  7.30nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50401387(CHEMBL2206445)
Affinity DataIC50:  9.23nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419424(CHEMBL1915730)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419430(CHEMBL1915738)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50401388(CHEMBL2206442)
Affinity DataIC50:  11.2nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50401389(CHEMBL2206441)
Affinity DataIC50:  11.2nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419440(CHEMBL1915734)
Affinity DataIC50:  12.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419427(CHEMBL1915735)
Affinity DataIC50:  15.8nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419429(CHEMBL1915737)
Affinity DataIC50:  15.8nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419422(CHEMBL1915728)
Affinity DataIC50:  19.9nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419433(CHEMBL1915743)
Affinity DataIC50:  19.9nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419432(CHEMBL1915741)
Affinity DataIC50:  31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419434(CHEMBL1915744)
Affinity DataIC50:  31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419435(CHEMBL1915745)
Affinity DataIC50:  31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419438(CHEMBL1915732)
Affinity DataIC50:  31.6nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419431(CHEMBL1915739)
Affinity DataIC50:  79.4nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419425(CHEMBL1915731)
Affinity DataIC50:  100nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50419441(CHEMBL1915740)
Affinity DataIC50:  100nMAssay Description:Inhibition of rat recombinant PDE10A expressed in baculovirus infected insect Sf9 cells using [3H]cAMP as substrate after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50357702(CHEMBL1915726)
Affinity DataIC50:  870nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50357701(CHEMBL1915725 | US9138494, Janssen B-3)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205237(9-(4-fluoro-3-hydroxymethylbutyl)guanine | CHEMBL2...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50210804(2-Amino-9-(4-hydroxy-3-hydroxymethyl-butyl)-1,9-di...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
TargetTranscriptional activator protein LuxR(Vibrio fischeri)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50389271(CHEMBL2063568)
Affinity DataIC50:  3.08E+5nMAssay Description:Antagonist activity at Vibrio fischeri LuxR-mediated quorum sensing expressed in Escherichia coli JB523 assessed as inhibition of C6-HSL-induced GFP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205236(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-fluoroethox...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205238(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(2-fluoropheny...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205239(3-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahyd...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205236(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-fluoroethox...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205241(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-fluoropheny...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205242(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-methoxyphen...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205242(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-methoxyphen...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205241(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-fluoropheny...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205238(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(2-fluoropheny...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205239(3-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahyd...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50228388(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-methoxyphen...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human cytosolic thymidine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50228386(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-hydroxyphen...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human cytosolic thymidine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50228389(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(4-(1-fluoroet...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human cytosolic thymidine kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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