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Found 24 with Last Name = 'chaurasia' and Initial = 's'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM14712((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...)
Affinity DataIC50:  20nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50440473(CHEMBL2425904)
Affinity DataIC50:  71nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50440474(CHEMBL2425903)
Affinity DataIC50:  140nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50440473(CHEMBL2425904)
Affinity DataIC50:  560nMAssay Description:Inhibition of CDK5/P25 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM12577(Bisphosphonate 2 | CHEMBL997 | JMC515594 Compound ...)
Affinity DataIC50:  640nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50440474(CHEMBL2425903)
Affinity DataIC50:  775nMAssay Description:Inhibition of CDK5/P25 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50440473(CHEMBL2425904)
Affinity DataIC50:  875nMAssay Description:Inhibition of CDK9/CyclinT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50440474(CHEMBL2425903)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50440473(CHEMBL2425904)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50054601(5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazole...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50440474(CHEMBL2425903)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of CDK9/CyclinT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM5566(2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidin...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50315414((5-(4-Phenylsulfonylfurazan-3-yloxy)-1-hydroxypent...)
Affinity DataIC50:  3.71E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50315415((5-(3-Phenylsulfonylfuroxan-4-yloxy)-1-hydroxypent...)
Affinity DataIC50:  7.95E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50335631(2-Nitro-3-oxo-3-[(4-trifluoromethyl)phenyl]aminopr...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50315412(5-(4-Phenylfurazan-3-yloxy)pentylidenebis(phosphon...)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50315413(5-(3-Phenylfuroxan-4-yloxy)pentylidenebis(phosphon...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50335629(2-Nitro-3-oxo-3-(biphenyl-4-yl)aminopropionitrile ...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50277785(4'-Amino-6'-methylsulfanyl-[1,1';2',1'']terphenyl-...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50335630(2-Hydroxyimino-3-oxo-3-[4-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50277825(4'-Amino-4,4''-dimethoxy-6'-methylsulfanyl-[1,1';2...)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50335632(2-Nitro-3-(4-nitrophenyl)amino-3-oxopropionitrile ...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50277824(4'-Amino-4-fluoro-2'',4''-dimethoxy-6'-methylsulfa...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of glucose-6-phosphatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50277823(4'-Amino-4''-methoxy-6'-methylsulfanyl-[1,1';2',1'...)
Affinity DataIC50:  8.60E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed