TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of CDK5/P25 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 775nMAssay Description:Inhibition of CDK5/P25 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 875nMAssay Description:Inhibition of CDK9/CyclinT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of CDK9/CyclinT (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 7.95E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillati...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of DHODH in Wistar rat liver homogenates by DCIP reduction assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of glucose-6-phosphatase (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair