TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMpH: 6.5Assay Description:Competitive inhibition of human recombinant PTB1B catalytic domain using pNPP substrate at 30 degC and pH 6.5 by Eadie-Hofstee plotMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant PTP1B catalytic domainMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of human recombinant PTP1B catalytic domainMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Inhibition of human recombinant PTP1B catalytic domainMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of human recombinant PTP1B catalytic domainMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
East China University of Science and Technology
East China University of Science and Technology
Affinity DataIC50: 2.90E+3nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMT: 2°CAssay Description:The assay mixture (100 ??L) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and PTP1B were monitored at 405 nm for 2 min at 30 ??C.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human CDC25B by pNPP hydrolysis assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.13E+3nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.85E+3nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.85E+3nMAssay Description:Inhibition of human recombinant PTP1B catalytic domainMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human recombinant PTP1B by pNPP hydrolysis assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMT: 2°CAssay Description:The assay mixture (100 ??L) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and PTP1B were monitored at 405 nm for 2 min at 30 ??C.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human recombinant PTB1B catalytic domain using pNPP substrateMore data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
East China University of Science and Technology
East China University of Science and Technology
Affinity DataIC50: 6.40E+3nMT: 2°CAssay Description:The assay mixture (100 ??L) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and PTP1B were monitored at 405 nm for 2 min at 30 ??C.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in CHO cells assessed as p-nitorphenol production after 2 mins by microplate readerMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant PTP1B by pNPP hydrolysis assayMore data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human CDC25B by pNPP hydrolysis assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human recombinant PTB1B catalytic domain using pNPP substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
East China University of Science and Technology
East China University of Science and Technology
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human TCPTP by pNPP hydrolysis assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human recombinant PTP1B by pNPP hydrolysis assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in CHO cells assessed as p-nitorphenol production after 2 mins by microplate readerMore data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human CDC25B by pNPP hydrolysis assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
East China University of Science and Technology
East China University of Science and Technology
Affinity DataIC50: 1.10E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMT: 2°CAssay Description:The assay mixture (100 ??L) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and PTP1B were monitored at 405 nm for 2 min at 30 ??C.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human recombinant PTP1B by pNPP hydrolysis assayMore data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of human CDC25B by pNPP hydrolysis assayMore data for this Ligand-Target Pair
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMT: 2°CAssay Description:The assay mixture (100 ??L) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and PTP1B were monitored at 405 nm for 2 min at 30 ??C.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
East China University of Science and Technology
East China University of Science and Technology
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
East China University of Science and Technology
East China University of Science and Technology
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human TCPTP by pNPP hydrolysis assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.27E+4nMT: 2°CAssay Description:The assay mixture (100 ??L) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and PTP1B were monitored at 405 nm for 2 min at 30 ??C.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
East China University of Science and Technology
East China University of Science and Technology
Affinity DataIC50: 1.45E+4nMT: 2°CAssay Description:The assay mixture (100 ??L) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and PTP1B were monitored at 405 nm for 2 min at 30 ??C.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of human recombinant PTB1B catalytic domain using pNPP substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of human SHP2 by pNPP hydrolysis assayMore data for this Ligand-Target Pair