Affinity DataKi: 0.200nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]naloxone from recombinant human MOR expressed in HEK cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced adenylyl cyclase-mediated cAMP accumulation after...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]naloxone from recombinant human MOR expressed in HEK cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]naloxone from recombinant human MOR expressed in HEK cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Displacement of [3H]naloxone from recombinant human MOR expressed in HEK cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.60nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-CP55940 from CB1 receptor in rat brain homogenate after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-CP55940 from CB1 receptor in rat brain homogenate after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Displacement of [3H]naloxone from recombinant human MOR expressed in HEK cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of [3H]-CP55940 from CB1 receptor in rat brain homogenate after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Displacement of [3H]naloxone from recombinant human MOR expressed in HEK cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]-CP55940 from CB1 receptor in rat brain homogenate after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Displacement of [3H]-CP55940 from CB1 receptor in rat brain homogenate after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 1.5 hrs by microbeta liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Displacement of [3H]naloxone from recombinant human MOR expressed in HEK cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair