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Found 221 with Last Name = 'chikkanna' and Initial = 'd'
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588385(US11542275, Compound 6)
Affinity DataIC50:  9nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558820(Isomer 1 of 1-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)...)
Affinity DataIC50:  10nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558802((R)-1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydro...)
Affinity DataIC50:  10nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588421(US11542275, Compound 43)
Affinity DataIC50:  10nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558800((R)-1-(4-(cyclopropylsulfonyl)benzyl)-3-(3-(3,4-di...)
Affinity DataIC50:  10nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588422(US11542275, Compound 44)
Affinity DataIC50:  11nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588395(US11542275, Compound 17)
Affinity DataIC50:  12nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588420(US11542275, Compound 42)
Affinity DataIC50:  12nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588424(US11542275, Compound 46)
Affinity DataIC50:  12nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588393(US11542275, Compound 15)
Affinity DataIC50:  12nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588414(US11542275, Compound 36)
Affinity DataIC50:  13nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588413(US11542275, Compound 35)
Affinity DataIC50:  14nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588411(US11542275, Compound 33)
Affinity DataIC50:  14nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588464(US11542275, Compound 89)
Affinity DataIC50:  15nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588394(US11542275, Compound 16)
Affinity DataIC50:  15nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588391(US11542275, Compound 13)
Affinity DataIC50:  17nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588430(US11542275, Compound 52)
Affinity DataIC50:  17nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588431(US11542275, Compound 53)
Affinity DataIC50:  18nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588434(US11542275, Compound 56)
Affinity DataIC50:  18nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588423(US11542275, Compound 45)
Affinity DataIC50:  18nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588450(US11542275, Compound 72)
Affinity DataIC50:  19nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588458(US11542275, Compound 81)
Affinity DataIC50:  19nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588405(US11542275, Compound 27)
Affinity DataIC50:  20nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558846((R)-1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydro...)
Affinity DataIC50:  20nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588381(US11542275, Compound 3)
Affinity DataIC50:  20nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588436(US11542275, Compound 58)
Affinity DataIC50:  20nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588466(US11542275, Compound 92)
Affinity DataIC50:  21nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588410(US11542275, Compound 32)
Affinity DataIC50:  22nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588463(US11542275, Compound 88)
Affinity DataIC50:  22nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588472(US11542275, Compound 100)
Affinity DataIC50:  24nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588428(US11542275, Compound 50)
Affinity DataIC50:  24nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588419(US11542275, Compound 41)
Affinity DataIC50:  25nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588439(US11542275, Compound 61)
Affinity DataIC50:  25nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588470(US11542275, Compound 98)
Affinity DataIC50:  25nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588396(US11542275, Compound 18)
Affinity DataIC50:  25nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588437(US11542275, Compound 59)
Affinity DataIC50:  25nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588452(US11542275, Compound 74)
Affinity DataIC50:  26nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588417(US11542275, Compound 39)
Affinity DataIC50:  26nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588382(US11542275, Compound 4)
Affinity DataIC50:  26nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558799((R)-1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydro...)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558791((R)-1-((5-(4,4-difluoropiperidine-1-carbonyl)pyrid...)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558747(1-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypr...)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558726(4-((3-(3-(3,4-dihydroisoquinolin-2(1H)-yl-2-hydrox...)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558801((R)-1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydro...)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558789((R)-1-((5-(3,3-difluoropyrrolidine-1-carbonylpyrid...)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558787((R)-1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydro...)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558840((R)-N-(6-((3-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-...)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588426(US11542275, Compound 48)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588387(US11542275, Compound 8)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588400(US11542275, Compound 22)
Affinity DataIC50:  31nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
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