Compile Data Set for Download or QSAR
maximum 50k data
Found 115 with Last Name = 'choi' and Initial = 'mj'
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human AXL using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506648(CHEMBL4445940)
Affinity DataIC50:  0.940nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50:  3nMAssay Description:Inhibition of human AuroraA using [H-LRRASLG] as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001935(CHEMBL3233601)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506636(CHEMBL4445646)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of human SYK using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001936(CHEMBL3233602)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  7nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001934(CHEMBL3233600)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001936(CHEMBL3233602)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of human PLK1 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50:  11nMAssay Description:Inhibition of human FAK using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001933(CHEMBL3233599)
Affinity DataIC50:  11nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50:  25nMAssay Description:Inhibition of human MER using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001933(CHEMBL3233599)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50:  50nMAssay Description:Inhibition of human TYRO3 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001935(CHEMBL3233601)
Affinity DataIC50:  53nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506657(CHEMBL4457670)
Affinity DataIC50:  80nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001934(CHEMBL3233600)
Affinity DataIC50:  85nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001931(CHEMBL3233597)
Affinity DataIC50:  450nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50305810(1H-3-(4-sulfamoylphenyl)-4-phenyl-pyrrole-2,5-dion...)
Affinity DataIC50:  610nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataIC50:  770nMAssay Description:Antagonist activity at 5HT3A receptor expressed in Xenopus oocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506649(CHEMBL4546231)
Affinity DataIC50:  790nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50295828(3-(4-methoxybenzyl)-2,4-dioxo-N-(2-(piperidin-1-yl...)
Affinity DataIC50:  800nMAssay Description:Antagonist activity at 5HT3A receptor expressed in Xenopus oocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  860nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001930(CHEMBL3233596)
Affinity DataIC50:  870nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506634(CHEMBL4441802)
Affinity DataIC50:  890nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001933(CHEMBL3233599)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins prior to substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins prior to substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001934(CHEMBL3233600)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins prior to substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001935(CHEMBL3233601)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins prior to substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001936(CHEMBL3233602)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins prior to substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50424306(CHEMBL2314485)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of mPGES1 (unknown origin) using PGH2 as substrate incubated for 30 mins prior to substrate addition by PGH2-coupled spectrophotometric an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001931(CHEMBL3233597)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50295834(3-(4-chlorobenzyl)-N-(3-morpholinopropyl)-2,4-diox...)
Affinity DataIC50:  1.30E+3nMAssay Description:Antagonist activity at 5HT3A receptor expressed in Xenopus oocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50295826(3-(2-methoxybenzyl)-2,4-dioxo-N-(2-(piperidin-1-yl...)
Affinity DataIC50:  1.40E+3nMAssay Description:Antagonist activity at 5HT3A receptor expressed in Xenopus oocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001930(CHEMBL3233596)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506644(CHEMBL4558560)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50295824(3-(4-methoxyphenyl)-2,4-dioxo-N-(2-(piperidin-1-yl...)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonist activity at 5HT3A receptor expressed in Xenopus oocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50295823(3-(4-fluorophenyl)-2,4-dioxo-N-(2-(piperidin-1-yl)...)
Affinity DataIC50:  1.90E+3nMAssay Description:Antagonist activity at 5HT3A receptor expressed in Xenopus oocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50196473(3-(4-fluorobenzyl)-2,4-dioxo-N-(2-(piperidin-1-yl)...)
Affinity DataIC50:  1.90E+3nMAssay Description:Antagonist activity at 5HT3A receptor expressed in Xenopus oocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50196475(3-(4-chlorobenzyl)-2,4-dioxo-N-(3-(piperidin-1-yl)...)
Affinity DataIC50:  1.95E+3nMAssay Description:Antagonist activity against T-type calcium channel alpha1GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50295829(3-cyclohexyl-2,4-dioxo-N-(2-(piperidin-1-yl)ethyl)...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at 5HT3A receptor expressed in Xenopus oocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50196465(3-(4-chlorobenzyl)-2,4-dioxo-N-(2-(piperidin-1-yl)...)
Affinity DataIC50:  2.08E+3nMAssay Description:Antagonist activity against T-type calcium channel alpha1GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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