Compile Data Set for Download or QSAR
maximum 50k data
Found 1048 with Last Name = 'colarusso' and Initial = 's'
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110121(3-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110121(3-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  0.0100nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110117(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{3...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110117(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{3...)
Affinity DataKi:  0.5nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110122((S)-4-((S)-2-Acetylamino-3-carboxy-propionylamino)...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110120(3-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  2nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110126(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{3...)
Affinity DataKi:  7nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150997(4-{2-[(S)-4,4-Difluoro-2-({(2S,4R)-1-((S)-2-isobut...)
Affinity DataKi:  20nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110125(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  30nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150993(4-[2-(4,4-Difluoro-2-{[(S)-(R)-1-(2-isobutoxycarbo...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50084685(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{3...)
Affinity DataKi:  40nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110125(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  40nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150992(CHEMBL366279 | {(S)-1-[(2S,4S)-4-Cyclohexyl-2-((S)...)
Affinity DataKi:  100nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110123(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  100nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150991(2-{3-[2-((S)-2-{[(2S,4S)-4-Cyclohexyl-1-((S)-2-iso...)
Affinity DataKi:  120nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110124(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-(1...)
Affinity DataKi:  150nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150989(CHEMBL362406 | {3-[2-((S)-2-{[(2S,4S)-4-Cyclohexyl...)
Affinity DataKi:  190nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150986((E)-3-{3-[2-((S)-4,4-Difluoro-2-{[(2S,4S)-1-((S)-2...)
Affinity DataKi:  350nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150990(4-[2-((S)-2-{[(R)-4-Cyclohexyl-1-((S)-2-isobutoxyc...)
Affinity DataKi:  350nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150994((E)-3-{3-[2-((S)-4,4-Difluoro-2-{[(2S,4S)-1-((S)-2...)
Affinity DataKi:  400nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150984(4-(2-{(S)-4,4-Difluoro-2-[(S)-2-((S)-2-isobutoxyca...)
Affinity DataKi:  400nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150995(CHEMBL263183 | [(S)-1-((2S,4S)-4-Cyclohexyl-2-{(S)...)
Affinity DataKi:  450nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50144349(4-[2-((S)-4,4-Difluoro-2-{[(2S,4S)-1-(2-isobutoxyc...)
Affinity DataKi:  450nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150983(2-{3-[2-((S)-2-{[(2S,4S)-4-Cyclohexyl-1-((S)-2-iso...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110128(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-(1...)
Affinity DataKi:  600nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122891(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataKi:  600nMAssay Description:Biinding affinity of the compound for enzyme NS3 protease wild-typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110127(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  640nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150996(CHEMBL181465 | {3-[2-((S)-2-{[(2S,4S)-4-Cyclohexyl...)
Affinity DataKi:  650nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110118(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  700nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122891(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataKi:  900nMAssay Description:Binding affinity for enzyme K136RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150985(CHEMBL362404 | {3-[2-((S)-4,4-Difluoro-2-{[(2S,4S)...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50144357(3-Chloro-4-(2-{(S)-4,4-difluoro-2-[(S)-2-((S)-2-is...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150988((E)-3-{3-[2-((S)-4,4-Difluoro-2-{[(2S,4S)-1-((S)-2...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122891(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataKi:  1.30E+3nMAssay Description:Biinding affinity of the compound for enzyme K136MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110119(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-(3...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of hepatitis C virus (HCV) NS3/NS4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122883(3-Chloro-4-(2-{4,4-difluoro-2-[2-(2-isobutoxycarbo...)
Affinity DataKi:  2.10E+3nMAssay Description:Biinding affinity of the compound for wild type NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122883(3-Chloro-4-(2-{4,4-difluoro-2-[2-(2-isobutoxycarbo...)
Affinity DataKi:  2.30E+3nMAssay Description:Biinding affinity of the compound for NS3 protease K136RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122883(3-Chloro-4-(2-{4,4-difluoro-2-[2-(2-isobutoxycarbo...)
Affinity DataKi:  4.00E+3nMAssay Description:Biinding affinity of the compound NS3 protease K136MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150987(4-[2-((S)-2-{[(R)-4-Benzyloxy-1-((S)-2-isobutoxyca...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50150987(4-[2-((S)-2-{[(R)-4-Benzyloxy-1-((S)-2-isobutoxyca...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibitory activity against Hepatitis C virus Non structural protein 3 serine protease/Non structural protein 4A serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi:  7.30E+3nMAssay Description:Biinding affinity of the compound for enzyme NS3 protease wild-typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi:  8.30E+3nMAssay Description:Binding affinity for enzyme K136RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi:  1.35E+4nMAssay Description:Biinding affinity of the compound for enzyme K136MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122891(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for enzyme human leukocyte HLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for enzyme human leukocyte HLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50051088(CHEMBL3318147)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of rat Nav1.7 stably expressed in cells with train pulses to -20 mV at 0.1 Hz and holding potential of -90 mV by whole-cell QPatch HT assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50122900((5R,8S,11S,14S,17S,20S)-20-acetamido-14-benzhydryl...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Irbm, Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50110122((S)-4-((S)-2-Acetylamino-3-carboxy-propionylamino)...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50051088(CHEMBL3318147)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human Nav1.7 stably expressed in cells with train pulses to -20 mV at 0.1 Hz and holding potential of -95 mV by whole-cell QPatch HT as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Irbm

Curated by ChEMBL
LigandPNGBDBM50547574(CHEMBL4747964)
Affinity DataIC50:  3nMAssay Description:Binding affinity to human KEAP1 Kelch domain (322 to 609 residues) incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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