Affinity DataKi: 5nMAssay Description:Binding affinity to adrenergic alpha1A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:Binding affinity to adrenergic alpha1A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 102nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 167nMAssay Description:Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 233nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 244nMAssay Description:Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 305nMAssay Description:Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 308nMAssay Description:Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 958nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.85E+3nMAssay Description:Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:Inhibition of 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.60E+3nMAssay Description:Inhibition of beta2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8.20E+3nMAssay Description:Inhibition of muscarinic receptor 3More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >2.20E+4nMAssay Description:Displacement of dofrtilide from human ERG channelMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Binding affinity to 5HT6 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Binding affinity to muscarinic M4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Binding affinity to muscarinic M3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Binding affinity to muscarinic M5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Binding affinity to 5HT1B receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity to adrenergic beta-2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity to 5-HT6 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity to 5-HT3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Antagonist activity at human muscarinic M4 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >2.23E+4nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair