Compile Data Set for Download or QSAR
maximum 50k data
Found 598 with Last Name = 'connelly' and Initial = 'mc'
TargetNEDD8-activating enzyme E1 catalytic subunit(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50285607(MLN-4924 | MLN-4924003 | Pevonedistat)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant His-tagged NAE1 expressed in baculovirus expression system after 90 mins in presence of FLAG-tagged NEDD8 by TR-FRET ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50145037(CHEMBL3765783)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of ATM (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50:  7nMAssay Description:Inhibition of ATM (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50208517(2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | C...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human ATM using p53 as substrate preincubated for 10 mins by ELISAMore data for this Ligand-Target Pair
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245154(CHEMBL4067795 | US11116757, No. A10)
Affinity DataIC50:  18nMAssay Description:Binding affinity for Adenosine A1 receptor using N-[3H] cyclohexyladenosine in rat forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50145038(CHEMBL2143829)
Affinity DataIC50:  20nMAssay Description:Inhibition of flag-tagged ATM (unknown origin) using p53 as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245237(CHEMBL4074213 | US11116757, No. A7)
Affinity DataIC50:  45nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245225(CHEMBL4099097 | US11116757, No. A15)
Affinity DataIC50:  50nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245227(CHEMBL4077431 | US11116757, No. A4)
Affinity DataIC50:  54nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245148(CHEMBL4077759 | US11116757, No. A6)
Affinity DataIC50:  58nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245225(CHEMBL4099097 | US11116757, No. A15)
Affinity DataIC50:  62nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245131(CHEMBL4094517 | US11116757, No. A5)
Affinity DataIC50:  68nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245153(CHEMBL4078685 | US11116757, No. A8)
Affinity DataIC50:  77nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245140(CHEMBL4103209 | US11116757, No. A11)
Affinity DataIC50:  82nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50389761(CHEMBL2070098)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human TRalpha assessed as inhibition of interaction with SRC2-2 by fluorescence polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245130(CHEMBL4086099 | US11116757, No. A13)
Affinity DataIC50:  112nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50460806(CHEMBL4226555 | US11116757, No. A88)
Affinity DataIC50:  140nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50460829(CHEMBL4225246 | US11116757, No. A30)
Affinity DataIC50:  170nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50389760(CHEMBL2070097)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human TRalpha assessed as inhibition of interaction with SRC2-2 by fluorescence polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50460827(CHEMBL4077751 | US11116757, No. A43)
Affinity DataIC50:  210nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245228(CHEMBL4065355 | US11116757, No. A42)
Affinity DataIC50:  241nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50208517(2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | C...)
Affinity DataIC50:  250nMAssay Description:Inhibition of ATM in human U2OS cells assessed as inhibition of p53 phosphorylation at Ser15 residueMore data for this Ligand-Target Pair
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245156(CHEMBL4079749 | US11116757, No. A45)
Affinity DataIC50:  256nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245142(CHEMBL4105639 | US11116757, No. A47)
Affinity DataIC50:  260nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50460825(CHEMBL4102019 | US11116757, No. A21)
Affinity DataIC50:  260nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245143(CHEMBL4087755 | US11116757, No. A57)
Affinity DataIC50:  290nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50389753(CHEMBL2070095)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at human TRalpha assessed as inhibition of interaction with SRC2-2 by fluorescence polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50208517(2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | C...)
Affinity DataIC50:  300nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245117(CHEMBL4077301 | US11116757, No. A35)
Affinity DataIC50:  304nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50460837(CHEMBL4103922 | US11116757, No. A58)
Affinity DataIC50:  310nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50389760(CHEMBL2070097)
Affinity DataIC50:  310nMAssay Description:Antagonist activity at human TRbeta assessed as inhibition of interaction with SRC2-2 after 3 hrs by fluorescence polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245118(CHEMBL4064579 | US11116757, No. A41)
Affinity DataIC50:  314nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245238(CHEMBL4103413 | US11116757, No. A28)
Affinity DataIC50:  325nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245226(CHEMBL4093853 | US11116757, No. A33)
Affinity DataIC50:  353nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245132(CHEMBL4102261 | US11116757, No. A50)
Affinity DataIC50:  356nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245210(CHEMBL4093655 | US11116757, No. A60)
Affinity DataIC50:  358nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50460836(CHEMBL4072130 | US11116757, No. A34)
Affinity DataIC50:  360nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50460835(CHEMBL4226839 | US11116757, No. A171)
Affinity DataIC50:  360nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50460847(CHEMBL4228742 | US11116757, No. A65)
Affinity DataIC50:  370nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Duke University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50145038(CHEMBL2143829)
Affinity DataIC50:  400nMAssay Description:Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50389767(CHEMBL2070236)
Affinity DataIC50:  430nMAssay Description:Antagonist activity at human TRalpha assessed as inhibition of interaction with SRC2-2 by fluorescence polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50389752(CHEMBL2070096)
Affinity DataIC50:  460nMAssay Description:Antagonist activity at human TRalpha assessed as inhibition of interaction with SRC2-2 by fluorescence polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245229(CHEMBL4102027 | US11116757, No. A67)
Affinity DataIC50:  481nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245214(CHEMBL4065590 | US11116757, No. A70)
Affinity DataIC50:  583nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245223(CHEMBL4085483 | US11116757, No. A26)
Affinity DataIC50:  612nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50460857(CHEMBL4224981 | US11116757, No. A102)
Affinity DataIC50:  620nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245152(CHEMBL4096706 | US11116757, No. A73)
Affinity DataIC50:  626nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245133(CHEMBL4084296 | US11116757, No. A74)
Affinity DataIC50:  654nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50389761(CHEMBL2070098)
Affinity DataIC50:  660nMAssay Description:Antagonist activity at human TRbeta assessed as inhibition of interaction with SRC2-2 after 3 hrs by fluorescence polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50460803(CHEMBL4225926 | US11116757, No. A79)
Affinity DataIC50:  660nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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