TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]bremazocine radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]U-69593. radioligandMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 91nMAssay Description:Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 456nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 523nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]bremazocine radioligandMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 530nMAssay Description:Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 630nMAssay Description:Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCPMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 680nMAssay Description:Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCPMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.37E+3nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.44E+3nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.54E+3nMAssay Description:Affinity of compound towards Dopamine receptor D2 was determined in presence of [3H](-)-sulpiride radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.62E+3nMAssay Description:Affinity of compound towards Sigma opioid receptor was determined in presence of [3H](+)-3-PPP radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.67E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]U-69593. radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 2.21E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]U-69593 radioligandMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes, Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 3.63E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]U-69593. radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 3.79E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 was determined in presence of [3H]U-69593. radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 6.99E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 labeled with [3H]bremazocine.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 7.21E+3nMAssay Description:Affinity of compound towards Opioid receptor kappa 1 labeled with [3H]bremazocine.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 7.35E+3nMAssay Description:Affinity of compound towards dopamine-D2 receptor was determined in presence of [3H](-)-sulpiride radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0450nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Binding ability towards opioid receptor delta expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding ability towards opioid receptor kappa expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Binding ability towards opioid receptor delta expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Binding ability towards opioid receptor delta expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Binding ability towards opioid receptor delta expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Binding affinity for sigma opioid receptor using [3H](+)-3-PPP as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptorMore data for this Ligand-Target Pair