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Found 207 with Last Name = 'coppo' and Initial = 'ft'
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM27725((2S)-2-[(3-{[(2-chloro-6-methylphenyl)carbamoyl]am...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243599((S)-2-cyclohexyl-2-(2-(3-(2,6-dichlorophenyl)ureid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243678((S)-2-(2-(3-(2,6-dimethylphenyl)ureido)-2-naphtham...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243601((S)-2-cyclohexyl-2-(2-(3-(2,6-dimethylphenyl)ureid...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194364(4-(4-cinnamamidobutyl)-N-(3,4-dichlorophenyl)-1,4-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243677((S)-2-(2-(3-(2,6-dichlorophenyl)ureido)-2-naphtham...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243352((S)-2-((S)-carboxy(2-(3-(2-chloro-6-methylphenyl)u...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243353((2S,3S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194380(CHEMBL223087 | N-(3,4-dichlorophenyl)-4-(3-(3-(3,4...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243599((S)-2-cyclohexyl-2-(2-(3-(2,6-dichlorophenyl)ureid...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243354((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243399((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243399((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human glycogen phosphorylase alpha in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243400((S)-4-amino-2-(2-(3-(2-chloro-6-methylphenyl)ureid...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243401((2S,3R)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194365(CHEMBL219730 | N-(3,4-dichlorophenyl)-4-(6-(3-(3,4...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243402((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194374(CHEMBL375397 | N-(3,4-dichlorophenyl)-4-(5-(3-(3,4...)
Affinity DataIC50:  470nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243444((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  520nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243445(2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-naphtha...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243446((S)-1-((S)-carboxy(2-(3-(2-chloro-6-methylphenyl)u...)
Affinity DataIC50:  580nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243640((S)-2-cyclohexyl-2-(2-(3-(2,6-diethylphenyl)ureido...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM27725((2S)-2-[(3-{[(2-chloro-6-methylphenyl)carbamoyl]am...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243447((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194375(CHEMBL373869 | N-(3,4-dichlorophenyl)-1-(5-(3-(3,4...)
Affinity DataIC50:  630nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243677((S)-2-(2-(3-(2,6-dichlorophenyl)ureido)-2-naphtham...)
Affinity DataIC50:  640nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243306((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194376(CHEMBL221226 | N-(3,4-dichlorophenyl)-4-(4-(3-(3,4...)
Affinity DataIC50:  710nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194370(CHEMBL220954 | N-(3-chloro-4-fluorophenyl)-4-(5-(3...)
Affinity DataIC50:  720nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243548((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-4,5-d...)
Affinity DataIC50:  860nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194363(CHEMBL221442 | N-(3,4-dichlorophenyl)-4-(5-(3-(3,4...)
Affinity DataIC50:  940nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194383(CHEMBL375832 | N-(3-chloro-4-fluorophenyl)-4-(5-(3...)
Affinity DataIC50:  980nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243601((S)-2-cyclohexyl-2-(2-(3-(2,6-dimethylphenyl)ureid...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243678((S)-2-(2-(3-(2,6-dimethylphenyl)ureido)-2-naphtham...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243353((2S,3S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243680((S)-2-(2-(3-o-tolylureido)-2-naphthamido)succinic ...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194381(CHEMBL373506 | N-(3-chlorophenyl)-4-(5-(3-(3,4-dic...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243488((S)-5-amino-2-(2-(3-(2-chloro-6-methylphenyl)ureid...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50194372(CHEMBL222729 | N-(4-chloro-3-(trifluoromethyl)phen...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human liver GPa in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243399((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in absence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243600((S)-2-cyclohexyl-2-(2-(2-(2,6-dichlorophenyl)aceta...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50242847((S)-2-(2-(3-(2-chlorophenyl)ureido)-2-naphthamido)...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243354((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243401((2S,3R)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50382046(CHEMBL2022737)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]Dofetilide from human ERG expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243305((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243305((S)-2-(2-(3-(2-chloro-6-methylphenyl)ureido)-2-nap...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243352((S)-2-((S)-carboxy(2-(3-(2-chloro-6-methylphenyl)u...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243446((S)-1-((S)-carboxy(2-(3-(2-chloro-6-methylphenyl)u...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243489((S)-6-amino-2-(2-(3-(2-chloro-6-methylphenyl)ureid...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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