Affinity DataKi: 0.0417nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.0537nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.0661nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.324nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.977nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-RX821002 from adrenergic alpha 2 receptor in post-mortem human brain frontal cortex membrane measured after 30 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 229nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 537nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 537nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 603nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 708nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.18E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.41E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.24E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.72E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
Affinity DataKi: 4.57E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 6.76E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 6.92E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 7.59E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 9.55E+3nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Displacement of [3H]-RX821002 from adrenergic alpha 2 receptor in post-mortem human brain frontal cortex membrane measured after 30 mins by liquid sc...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: 1.54E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer compl...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: 1.59E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer compl...More data for this Ligand-Target Pair
Affinity DataKi: 1.86E+4nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase G190A mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer compl...More data for this Ligand-Target Pair
Affinity DataKi: 2.57E+4nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 2.63E+4nMAssay Description:Displacement of [3H]-RX821002 from adrenergic alpha 2 receptor in post-mortem human brain frontal cortex membrane measured after 30 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 4.27E+4nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 4.68E+4nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 4.90E+4nMAssay Description:Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Barcelona
Curated by ChEMBL
University Of Barcelona
Curated by ChEMBL
Affinity DataKi: 6.17E+4nMAssay Description:Displacement of [3H]-RX821002 from adrenergic alpha 2 receptor in post-mortem human brain frontal cortex membrane measured after 30 mins by liquid sc...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: 6.33E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer compl...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: 6.76E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase V106A mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer compl...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: 6.99E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C mutant using radioactively-labeled [alpha-32P]ATP substrate and activated DNA as template-primer...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Volgograd State Medical University
Curated by ChEMBL
Volgograd State Medical University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase p66/p51 pre-incubated with compound before enzyme addition using poly(rA) template and...More data for this Ligand-Target Pair