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Found 33 with Last Name = 'dang' and Initial = 'y'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50403297(CHEMBL5288854)
Affinity DataKi:  3.70nMAssay Description:The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50594741(CHEMBL5205088)
Affinity DataIC50:  1nMAssay Description:The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50403296(CHEMBL5284935)
Affinity DataIC50:  2nMAssay Description:Compound was evaluated for the inhibition of Escherichia coli Thymidylate SynthaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50403300(CHEMBL5282505)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50403299(CHEMBL5276895)
Affinity DataIC50:  5nMAssay Description:The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50403296(CHEMBL5284935)
Affinity DataIC50:  6nMAssay Description:Compound was evaluated for the inhibition of Escherichia coli Thymidylate SynthaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50106301(CHEMBL3598140)
Affinity DataIC50:  7nMAssay Description:Compound was evaluated for the inhibition of Escherichia coli Thymidylate SynthaseMore data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50403298(CHEMBL5187263)
Affinity DataIC50:  13nMAssay Description:The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1)More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50594741(CHEMBL5205088)
Affinity DataIC50:  13nMAssay Description:The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50594741(CHEMBL5205088)
Affinity DataIC50:  32nMAssay Description:The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50594741(CHEMBL5205088)
Affinity DataIC50:  35nMAssay Description:Compound was evaluated for the inhibition of Escherichia coli Thymidylate SynthaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50403297(CHEMBL5288854)
Affinity DataIC50:  221nMAssay Description:The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68281(Bengamide A)
Affinity DataIC50:  1.90E+3nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68286(Bengamide N | Bengamide O)
Affinity DataIC50:  2.70E+3nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Guizhou Medcial University

Curated by ChEMBL
LigandPNGBDBM50068270((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...)
Affinity DataIC50:  5.18E+3nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68285(Bengamide M)
Affinity DataIC50:  5.40E+3nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68281(Bengamide A)
Affinity DataIC50:  1.05E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68282(Bengamide B)
Affinity DataIC50:  1.79E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68283(Bengamide G)
Affinity DataIC50:  2.68E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68282(Bengamide B)
Affinity DataIC50:  2.93E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68284(Bengamide L)
Affinity DataIC50:  3.71E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68286(Bengamide N | Bengamide O)
Affinity DataIC50:  4.02E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68286(Bengamide N | Bengamide O)
Affinity DataIC50: >5.00E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68283(Bengamide G)
Affinity DataIC50: >5.00E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68284(Bengamide L)
Affinity DataIC50: >5.00E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68285(Bengamide M)
Affinity DataIC50: >5.00E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
The Johns Hopkins University

LigandPNGBDBM68286(Bengamide N | Bengamide O)
Affinity DataIC50: >5.00E+4nMAssay Description:The determined effects of seven bengamide analogs on the enzymatic activity of both recombinated human MetAP1 and MetAP2 in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Guizhou Medcial University

Curated by ChEMBL
LigandPNGBDBM50068270((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...)
Affinity DataIC50:  7.69E+4nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Guizhou Medcial University

Curated by ChEMBL
LigandPNGBDBM50068270((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of IDH1 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Guizhou Medcial University

Curated by ChEMBL
LigandPNGBDBM50068270((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...)
Affinity DataKd:  1.28E+4nMAssay Description:Binding affinity to IDH1 R132H mutant (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Guizhou Medcial University

Curated by ChEMBL
LigandPNGBDBM50068270((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to IDH1 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Guizhou Medcial University

Curated by ChEMBL
LigandPNGBDBM50068270((E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-y...)
Affinity DataKd:  2.81E+3nMAssay Description:Binding affinity to IDH1 R132C mutant (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50153594(CHEMBL3774855)
Affinity DataEC50:  160nMAssay Description:Compound was evaluated for the inhibition of Escherichia coli Thymidylate SynthaseMore data for this Ligand-Target Pair