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Found 48 with Last Name = 'daulatabad' and Initial = 'av'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334248(1-(4-Isopropylbenzenesulfonyl)-3-(4-methylpiperazi...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334254(5-Bromo-1-(3-chlorobenzenesulfonyl)-3-(4-methylpip...)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334253(3-(4-ethylpiperazin-1-yl)-1-(4-isopropylphenylsulf...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334255(5-Bromo-1-(4-fluorobenzenesulfonyl)-3-(4-methylpip...)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334259(5-Bromo-1-(2-bromobenzenesulfonyl)-3-(4-methylpipe...)
Affinity DataKi:  10.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334256(5-Bromo-1-(4-fluorobenzenesulfonyl)-3-(4-ethylpipe...)
Affinity DataKi:  10.6nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334260(5-Chloro-1-(4-fluorobenzenesulfonyl)-3-(4-ethylpip...)
Affinity DataKi:  10.7nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334250(1-(3-chlorophenylsulfonyl)-3-(4-methylpiperazin-1-...)
Affinity DataKi:  10.8nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334249(1-(4-Fluorobenzenesulfonyl)-3-(4-methylpiperazin-1...)
Affinity DataKi:  11.8nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334251(1-(2-bromophenylsulfonyl)-3-(4-methylpiperazin-1-y...)
Affinity DataKi:  15.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334252(3-(4-methylpiperazin-1-yl)-1-(phenylsulfonyl)-1H-i...)
Affinity DataKi:  15.9nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334261(5-Chloro-1-(2-bromobenzenesulfonyl)-3-(4-ethylpipe...)
Affinity DataKi:  20.3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334257(5-Bromo-1-(4-isopropylbenzenesulfonyl)-3-(4-methyl...)
Affinity DataKi:  23.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334266(6-Chloro-1-(2-naphthylsulfonyl)-3-(4-ethylpiperazi...)
Affinity DataKi:  25.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334258(5-Bromo-1-(4-isopropylbenzenesulfonyl)-3-(4-ethylp...)
Affinity DataKi:  30.1nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334267(6-Chloro-1-(2-bromobenzenesulfonyl)-3-(4-methylpip...)
Affinity DataKi:  30.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334262(5-Chloro-1-(4-isopropylbenzenesulfonyl)-3-(4-ethyl...)
Affinity DataKi:  30.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334264(6-Chloro-1-(4-isopropylbenzenesulfonyl)-3-(4-methy...)
Affinity DataKi:  55.3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334265(6-Chloro-1-(2,5-dimethoxybenzenesulfonyl)-3-(4-eth...)
Affinity DataKi:  63.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334263(6-Chloro-1-(4-methoxybenzenesulfonyl)-3-(4-ethylpi...)
Affinity DataKi:  82.3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM234385(2-Methoxy-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4b...)
Affinity DataKi:  127nM ΔG°:  -40.9kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60–80 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM234384(2-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataKi:  464nM ΔG°:  -37.6kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60–80 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM234386(1-Fluoro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataKi: >500nM ΔG°: >-37.4kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60–80 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334249(1-(4-Fluorobenzenesulfonyl)-3-(4-methylpiperazin-1...)
Affinity DataIC50:  292nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334248(1-(4-Isopropylbenzenesulfonyl)-3-(4-methylpiperazi...)
Affinity DataIC50:  310nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334254(5-Bromo-1-(3-chlorobenzenesulfonyl)-3-(4-methylpip...)
Affinity DataIC50:  322nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334255(5-Bromo-1-(4-fluorobenzenesulfonyl)-3-(4-methylpip...)
Affinity DataIC50:  1.53E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334260(5-Chloro-1-(4-fluorobenzenesulfonyl)-3-(4-ethylpip...)
Affinity DataIC50:  1.78E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334255(5-Bromo-1-(4-fluorobenzenesulfonyl)-3-(4-methylpip...)
Affinity DataIC50:  4.61E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334249(1-(4-Fluorobenzenesulfonyl)-3-(4-methylpiperazin-1...)
Affinity DataIC50:  4.77E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50:  5.06E+3nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334248(1-(4-Isopropylbenzenesulfonyl)-3-(4-methylpiperazi...)
Affinity DataIC50:  5.54E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50:  7.65E+3nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50323062(CHEMBL1210648 | N-(3,5-Dichloro-2-methoxyphenyl)-4...)
Affinity DataIC50:  8.44E+3nMAssay Description:Inhibition of human CY3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50323061(CHEMBL1210646 | N-(2-Bromophenyl)-4-ethyl-3-[(1-me...)
Affinity DataIC50:  9.62E+3nMAssay Description:Inhibition of human CY3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50: >1.00E+4nMAssay Description:Muscarinic acetylcholine receptor M1 was cloned into an expression vector and transfected in CHO cells along with CRE-Luc reporter system. Isolated c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Suven Life Sciences

LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: >1.00E+4nMAssay Description:CHO cells were transfected with an expression vector encoding rat 5-HT7 gene and CRE-Luc reporter system. Colonies were isolated and screened with 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Suven Life Sciences

LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50: >1.00E+4nMAssay Description:CHO cells were transfected with an expression vector encoding rat 5-HT7 gene and CRE-Luc reporter system. Colonies were isolated and screened with 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: >1.00E+4nMAssay Description:Muscarinic acetylcholine receptor M1 was cloned into an expression vector and transfected in CHO cells along with CRE-Luc reporter system. Isolated c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant CHO cells were established by transfecting an expression vector encoding human 5-HT4a gene and CRE-Luc reporter system. Isolated colonies...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant CHO cells were established by transfecting an expression vector encoding human 5-HT4a gene and CRE-Luc reporter system. Isolated colonies...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM50334249(1-(4-Fluorobenzenesulfonyl)-3-(4-methylpiperazin-1...)
Affinity DataIC50:  2.64E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM50334255(5-Bromo-1-(4-fluorobenzenesulfonyl)-3-(4-methylpip...)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50:  3.71E+4nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM50334248(1-(4-Isopropylbenzenesulfonyl)-3-(4-methylpiperazi...)
Affinity DataIC50:  3.92E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM50323062(CHEMBL1210648 | N-(3,5-Dichloro-2-methoxyphenyl)-4...)
Affinity DataIC50:  4.18E+4nMAssay Description:Inhibition of human CY2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Suven Life Sciences

LigandPNGBDBM50323061(CHEMBL1210646 | N-(2-Bromophenyl)-4-ethyl-3-[(1-me...)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition of human CY2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: >4.50E+4nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed