Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.6nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.7nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.8nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 11.8nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 15.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 15.9nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 20.3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 23.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 25.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 30.1nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 30.2nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 30.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 55.3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 63.5nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 82.3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 127nM ΔG°: -40.9kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (6080 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Affinity DataKi: 464nM ΔG°: -37.6kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (6080 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Affinity DataKi: >500nM ΔG°: >-37.4kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (6080 Ci/mmol), respectively. The ...More data for this Ligand-Target Pair
Affinity DataIC50: 292nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 322nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 4.61E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 4.77E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 5.06E+3nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 7.65E+3nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Affinity DataIC50: 8.44E+3nMAssay Description:Inhibition of human CY3A4More data for this Ligand-Target Pair
Affinity DataIC50: 9.62E+3nMAssay Description:Inhibition of human CY3A4More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Muscarinic acetylcholine receptor M1 was cloned into an expression vector and transfected in CHO cells along with CRE-Luc reporter system. Isolated c...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:CHO cells were transfected with an expression vector encoding rat 5-HT7 gene and CRE-Luc reporter system. Colonies were isolated and screened with 10...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:CHO cells were transfected with an expression vector encoding rat 5-HT7 gene and CRE-Luc reporter system. Colonies were isolated and screened with 10...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Muscarinic acetylcholine receptor M1 was cloned into an expression vector and transfected in CHO cells along with CRE-Luc reporter system. Isolated c...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant CHO cells were established by transfecting an expression vector encoding human 5-HT4a gene and CRE-Luc reporter system. Isolated colonies...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Recombinant CHO cells were established by transfecting an expression vector encoding human 5-HT4a gene and CRE-Luc reporter system. Isolated colonies...More data for this Ligand-Target Pair
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 3.71E+4nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
Affinity DataIC50: 3.92E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 4.18E+4nMAssay Description:Inhibition of human CY2D6More data for this Ligand-Target Pair
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition of human CY2D6More data for this Ligand-Target Pair
Affinity DataIC50: >4.50E+4nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair