Found 120 with Last Name = 'de lemos' and Initial = 'e' TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 40nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£
Curated by ChEMBL
Institut National De La Sant£
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [G550E](Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 102nMAssay Description:YFP-Halide Influx Assay for the CFTR-ΔF508 Mutation and Suppressor mutants (I539T or G550E)The YFP halide influx assay measures the functionalit...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 103nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 104nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 116nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 138nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 156nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 227nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 245nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 247nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 256nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 261nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 263nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
