Affinity DataKi: 0.25nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Universita Degli Studi Di Milano
Universita Degli Studi Di Milano
Affinity DataKi: 25nM ΔG°: -43.1kJ/mole IC50: 460nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Universita Degli Studi Di Milano
Universita Degli Studi Di Milano
Affinity DataKi: 61nM ΔG°: -40.9kJ/mole IC50: 530nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 145nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 198nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 220nM ΔG°: -37.6kJ/mole IC50: 250nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 250nM ΔG°: -37.3kJ/mole IC50: 270nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 265nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 420nM ΔG°: -36.0kJ/mole IC50: 460nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 870nM ΔG°: -34.2kJ/mole IC50: 970nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader (Tecan) at excitation and emission wavelengths of 485 and 530 nm, respectively. The e...More data for this Ligand-Target Pair
Affinity DataKi: 1.78E+3nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 1.85E+3nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 2.25E+3nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 3.65E+3nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 4.85E+3nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of 9 (2nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]-dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Fondazione Irccs Istituto Nazionale Dei Tumori
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair