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Found 59 with Last Name = 'deslandes' and Initial = 's'
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50216171(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  45nMAssay Description:Inhibition of POP in human HCEC cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  45nMAssay Description:Inhibition of POP in human LNZ308 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  45nMAssay Description:Inhibition of POP in human LN229 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393844(CHEMBL2159745)
Affinity DataIC50:  65nMAssay Description:Inhibition of POP in human HCEC cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393844(CHEMBL2159745)
Affinity DataIC50:  68nMAssay Description:Inhibition of POP in human LN18 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393844(CHEMBL2159745)
Affinity DataIC50:  68nMAssay Description:Inhibition of POP in human LN229 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393844(CHEMBL2159745)
Affinity DataIC50:  73nMAssay Description:Inhibition of POP in human LNZ308 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  81nMAssay Description:Inhibition of POP in human LN18 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385583(CHEMBL2041917)
Affinity DataIC50:  90nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385585(CHEMBL2041919)
Affinity DataIC50:  130nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  150nMAssay Description:Inhibition at human recombinant POPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385583(CHEMBL2041917)
Affinity DataIC50:  180nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  200nMAssay Description:Inhibition of POP in intact human LNZ308 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50216159(5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...)
Affinity DataIC50:  200nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393844(CHEMBL2159745)
Affinity DataIC50:  250nMAssay Description:Inhibition of POP in intact human LN18 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50216159(5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...)
Affinity DataIC50:  260nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393844(CHEMBL2159745)
Affinity DataIC50:  290nMAssay Description:Inhibition of POP in intact human HCEC cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393844(CHEMBL2159745)
Affinity DataIC50:  290nMAssay Description:Inhibition of POP in intact human LNZ308 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385580(CHEMBL2041914)
Affinity DataIC50:  300nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  300nMAssay Description:Inhibition of POP in intact human LN18 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385585(CHEMBL2041919)
Affinity DataIC50:  310nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  350nMAssay Description:Inhibition of POP in human LNZ308 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385584(CHEMBL2041918)
Affinity DataIC50:  420nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  450nMAssay Description:Inhibition of POP in intact human LN229 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393844(CHEMBL2159745)
Affinity DataIC50:  500nMAssay Description:Inhibition of POP in intact human LN229 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393843(CHEMBL2159748)
Affinity DataIC50:  500nMAssay Description:Inhibition of POP in intact human HCEC cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  500nMAssay Description:Inhibition of POP in human LN229 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385583(CHEMBL2041917)
Affinity DataIC50:  510nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50216171(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)
Affinity DataIC50:  520nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  580nMAssay Description:Inhibition of POP in intact human LN18 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  610nMAssay Description:Inhibition of POP in intact human LN229 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  620nMAssay Description:Inhibition of POP in human HCEC cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  620nMAssay Description:Inhibition of POP in human LN18 cell extracts using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  640nMAssay Description:Inhibition of POP in intact human LNZ308 cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50393842(CHEMBL2159749)
Affinity DataIC50:  680nMAssay Description:Inhibition of POP in intact human HCEC cells using Cbz-Gly-Pro-AMC substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385584(CHEMBL2041918)
Affinity DataIC50:  910nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50216171(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385585(CHEMBL2041919)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385579(CHEMBL2041749)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385584(CHEMBL2041918)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385580(CHEMBL2041914)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50216171(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50216159(5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385581(CHEMBL2041915)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385580(CHEMBL2041914)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385579(CHEMBL2041749)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385579(CHEMBL2041749)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385578(CHEMBL2041912)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385578(CHEMBL2041912)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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