Compile Data Set for Download or QSAR
maximum 50k data
Found 101 with Last Name = 'di marco' and Initial = 's'
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169942(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(4-methanesu...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169930(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[(cyclopropylme...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169904(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(4-diethylam...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against hepatitis C virus NS5B polymerase enzyme; Range=6-9 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169911(3-Cyclohexyl-1-[2-(2-diethylaminomethyl-morpholin-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against hepatitis C virus NS5B polymerase enzyme; Range=6-9 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169899(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against hepatitis C virus NS5B polymerase enzyme; Range=6-9 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169922(3-Cyclohexyl-1-[2-(4-diethylamino-piperidin-1-yl)-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against hepatitis C virus NS5B polymerase enzyme; Range=6-9 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169906(3-Cyclohexyl-1-[2-(2-diethylaminomethyl-morpholin-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against hepatitis C virus NS5B polymerase enzyme; Range=6-9 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169915(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(1,1-dioxo-1...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169903(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[(isopropyl-met...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169920(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(4-methyl-pi...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169931(2-(4-Chloro-phenyl)-3-cyclohexyl-1-{[methyl-(1-met...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169919(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[2-(4-dimethyla...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35570(1H-benzo[de]isoquinoline-1,3(2H)-dione, 19)
Affinity DataIC50: <14nM EC50:  2.20E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [2420-2989,M2833T,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169932(2-(4-Chloro-phenyl)-3-cyclohexyl-1-[(dimethylcarba...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169921(3-Cyclohexyl-2-[3-(3,3-difluoro-piperidin-1-ylmeth...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169916(3-Cyclohexyl-1-{[methyl-(1-methyl-piperidin-3-ylme...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169929(2-Cyclohex-1-enyl-3-cyclohexyl-1-[2-(4-dimethylami...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169910(3-Cyclohexyl-1-[2-(4-methanesulfonyl-piperazin-1-y...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35563(1H-benzo[de]isoquinoline-1,3(2H)-dione, 12)
Affinity DataIC50:  19nM EC50:  3.80E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50:  20nM EC50:  7.10E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-2989,P2914A,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35560(1H-benzo[de]isoquinoline-1,3(2H)-dione, 9)
Affinity DataIC50:  24nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35558(1H-benzo[de]isoquinoline-1,3(2H)-dione, 7)
Affinity DataIC50:  29nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35569(1H-benzo[de]isoquinoline-1,3(2H)-dione, 18)
Affinity DataIC50:  30nM EC50:  1.90E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169927(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-furan-3-y...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169933(3-Cyclohexyl-1-[2-(4-methyl-piperazin-1-yl)-2-oxo-...)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [2420-2989,P2914A,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169898(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Affinity DataIC50:  41nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35571(1H-benzo[de]isoquinoline-1,3(2H)-dione, 20 | cis-i...)
Affinity DataIC50:  42nM EC50:  3.80E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 2b (isolate HC-J8) (HCV...)
Irbm, Mrl Rome

LigandPNGBDBM35570(1H-benzo[de]isoquinoline-1,3(2H)-dione, 19)
Affinity DataIC50:  43nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169907(3-Cyclohexyl-1-[2-(1,1-dioxo-1lambda*6*-thiomorpho...)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169938(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Affinity DataIC50:  47nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169908(3-Cyclohexyl-1-[2-(4-dimethylamino-piperidin-1-yl)...)
Affinity DataIC50:  49nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162102(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-phenyl-1H...)
Affinity DataIC50:  59nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169946(3-Cyclohexyl-1-[(isopropyl-methyl-carbamoyl)-methy...)
Affinity DataIC50:  62nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169924(3-Cyclohexyl-1-[(cyclopropylmethyl-carbamoyl)-meth...)
Affinity DataIC50:  63nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50:  64nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35567(1H-benzo[de]isoquinoline-1,3(2H)-dione, 16)
Affinity DataIC50:  66nM EC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169928(3-Cyclopentyl-1-[2-(4-methyl-piperazin-1-yl)-2-oxo...)
Affinity DataIC50:  68nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169917(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-(6-methox...)
Affinity DataIC50:  69nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169918(3-Cyclohexyl-1-[2-(4-dimethylamino-pyrrolidin-2-yl...)
Affinity DataIC50:  71nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169912(2,3-Dicyclohexyl-1-[2-(4-dimethylamino-piperidin-1...)
Affinity DataIC50:  72nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169905(3-Cyclopentyl-1-[2-(4-dimethylamino-pyrrolidin-2-y...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169913(3-Cyclohexyl-1-dimethylcarbamoylmethyl-2-{3-[(isop...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [2420-2989,M2833T,R2963Q](Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50:  78nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169900(2-(4-Chloro-3-dimethylaminomethyl-phenyl)-3-cycloh...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 2b (isolate HC-J8) (HCV...)
Irbm, Mrl Rome

LigandPNGBDBM35566(1H-benzo[de]isoquinoline-1,3(2H)-dione, 15)
Affinity DataIC50:  90nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50169901(3-Cyclohexyl-1-[(dimethylcarbamoylmethyl-methyl-ca...)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against by hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 101 total ) | Next | Last >>
Jump to: