Compile Data Set for Download or QSAR
maximum 50k data
Found 1958 with Last Name = 'dou' and Initial = 'd'
TargetD(1A) dopamine receptor(RAT)
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM82247(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)
Affinity DataKi:  0.430nMAssay Description:Inhibition of [3H]SCH-23,390 binding to Dopamine receptor D1 at 0.25 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079375(CHEMBL3417008 | US9663465, 20)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Homo sapiens (Human))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50056221(CHEMBL3322297)
Affinity DataKi:  1.60nMAssay Description:Inhibition of glycogen phosphorylase b (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50063920((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataKi:  2nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50063920((R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propy...)
Affinity DataKi:  2nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079377(CHEMBL3417007)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50004796(8-Chloro-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of [3H]SCH-23,390 binding to Dopamine receptor D1 at 0.25 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079367(CHEMBL3416998)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079365(CHEMBL3416996 | US9663465, 8)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079366(CHEMBL3416997 | US9663465, 12)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079369(CHEMBL3417000 | US9663465, 11)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143826((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  5nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 at 0.02 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Wichita State University

Curated by ChEMBL
LigandPNGBDBM50376931(CHEMBL260190)
Affinity DataKi:  5.5nMAssay Description:Inhibition human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143826((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  6nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143826((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  6nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50038349((S)-6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-...)
Affinity DataKi:  6.60nMAssay Description:Inhibition of [3H]SCH-23,390 binding to Dopamine receptor D1 at 0.25 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079368(CHEMBL3416999 | US9663465, 16)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079364(CHEMBL3416995 | US9663465, 7)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM84950(CAS_183782 | NSC_183782 | RS 67333)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103099((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  11nMAssay Description:Inhibitionof Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173960((2S,4S)-1-((R)-2-amino-3-methyl-3-(pyridin-2-ylmet...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50022051(1-Phenyl-6-chloro-7-hydroxy-N-methyl-1,2,3,4-tetra...)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]SCH-23,390 binding to Dopamine receptor D1 at 0.25 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50200721((R)-1-(2-(cyclohexanecarboxamido)acetyl)pyrrolidin...)
Affinity DataKi:  14nMAssay Description:Inhibition of FAP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079370(CHEMBL3417001)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079363(CHEMBL3414597 | US9663465, 6)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103097((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  16nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103097((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  16nMAssay Description:Inhibitionof Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103092((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  17nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103102((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  17nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103096((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  17nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173976((2S,4S)-1-((R)-2-amino-3-methyl-3-(pyridin-3-ylmet...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143825(5-[1-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-na...)
Affinity DataKi:  20nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143827((E)-3-[4-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,8-te...)
Affinity DataKi:  20nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079371(CHEMBL3417002)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103098((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  20nMAssay Description:Inhibitionof Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103093((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  20nMAssay Description:Inhibitionof Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079372(CHEMBL3417003)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103092((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  21nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173983((2S,4S)-1-((R)-2-amino-3-methyl-3-(3-phenylpropylt...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103099((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  24nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50148913(CHEMBL3770455)
Affinity DataKi:  26nMAssay Description:Competitive inhibition of His6-tagged human liver glycogen phosphorylase-a expressed in Escherichia coli BL21 Gold (DE3) assessed as release of inorg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103102((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  27nMAssay Description:Inhibitionof Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103098((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  27nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Homo sapiens (Human))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50402338(CHEMBL401150)
Affinity DataKi:  27nMAssay Description:Inhibition of RNase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103097((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  28nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103093((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  29nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103095((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  29nMAssay Description:Inhibitionof Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173981((2S,4S)-1-((R)-3-(4-methoxybenzylthio)-2-amino-3-m...)
Affinity DataKi:  29nMAssay Description:Inhibitory activity against human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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