BindingDB PrimarySearch_ki

Found 259 with Last Name = 'dubrovskyi' and Initial = 'o'

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539801(CHEMBL4648912 | US11840533, Compound 70)

IC50: 1.70nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 2 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539801(CHEMBL4648912 | US11840533, Compound 70)

IC50: 5.90nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539804(CHEMBL4640025 | US11840533, Compound 71)

IC50: 8.30nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539802(CHEMBL4647718)

IC50: 9.40nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539800(CHEMBL4632358)

IC50: 13nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 2 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539803(CHEMBL4633289)

IC50: 13nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539800(CHEMBL4632358)

IC50: 13nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50031720((Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-p...)

IC50: 15nMAssay Description:Inhibition of human ERG stably expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539804(CHEMBL4640025 | US11840533, Compound 71)

IC50: 22nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 2 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539805(CHEMBL4644032 | US11840533, Compound 72)

IC50: 40nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539786(CHEMBL4640133)

IC50: 48nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539792(CHEMBL4646027)

IC50: 54nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539803(CHEMBL4633289)

IC50: 63nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 2 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539799(CHEMBL4638621)

IC50: 83nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539791(CHEMBL4637378)

IC50: 89nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539785(CHEMBL4646327)

IC50: 96nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496864(SARS-CoV-2 PLpro Inhibitor, 94)

IC50: 113nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)

IC50: 126nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 2 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539793(CHEMBL4644443)

IC50: 158nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539798(CHEMBL4649774)

IC50: 161nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496858(SARS-CoV-2 PLpro Inhibitor, 88)

IC50: 170nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539796(CHEMBL4632925)

IC50: 174nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539794(CHEMBL4647786)

IC50: 175nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539797(CHEMBL4635722)

IC50: 180nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)

IC50: 199nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496862(SARS-CoV-2 PLpro Inhibitor, 92)

IC50: 210nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539805(CHEMBL4644032 | US11840533, Compound 72)

IC50: 220nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 2 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496865(SARS-CoV-2 PLpro Inhibitor, 95)

IC50: 250nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496856(SARS-CoV-2 PLpro Inhibitor, 86)

IC50: 330nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496859(SARS-CoV-2 PLpro Inhibitor, 89)

IC50: 370nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Details Article PubMed PDB

3D Structure (crystal)

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496842(SARS-CoV-2 PLpro Inhibitor, 72)

IC50: 390nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496861(SARS-CoV-2 PLpro Inhibitor, 91)

IC50: 410nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496863(SARS-CoV-2 PLpro Inhibitor, 93)

IC50: 430nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496843(SARS-CoV-2 PLpro Inhibitor, 73)

IC50: 560nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496835(SARS-CoV-2 PLpro Inhibitor, 65)

IC50: 590nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496522(SARS-CoV-2 PLpro Inhibitor, 6)

IC50: 600nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

PNG

BDBM50539795(CHEMBL4639392)

IC50: 600nMAssay Description:Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496857(SARS-CoV-2 PLpro Inhibitor, 87)

IC50: 620nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496860(SARS-CoV-2 PLpro Inhibitor, 90)

IC50: 640nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496851(SARS-CoV-2 PLpro Inhibitor, 81)

IC50: 640nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496555(SARS-CoV-2 PLpro Inhibitor, 9)

IC50: 700nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496854(SARS-CoV-2 PLpro Inhibitor, 84)

IC50: 700nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496844(SARS-CoV-2 PLpro Inhibitor, 74)

IC50: 750nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496847(SARS-CoV-2 PLpro Inhibitor, 77 | SARS-CoV-2 PLpro ...)

IC50: 760nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496554(SARS-CoV-2 PLpro Inhibitor, 8)

IC50: 800nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496797(SARS-CoV-2 PLpro Inhibitor, 27)

IC50: 800nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496846(SARS-CoV-2 PLpro Inhibitor, 76)

IC50: 810nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496866(SARS-CoV-2 PLpro Inhibitor, 96)

IC50: 810nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496850(SARS-CoV-2 PLpro Inhibitor, 80)

IC50: 820nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Replicase polyprotein 1ab(2019-nCoV)
University of Illinois At Chicago

PNG

BDBM496839(SARS-CoV-2 PLpro Inhibitor, 69)

IC50: 900nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Displayed 1 to 50 (of 259 total ) | Next | Last >>

Filter my 259 hits

Targets 31▿
- Replicase polyprotein 1ab 186
- Bromodomain-containing protein 4 32
- Bromodomain-containing protein 3 3
- Angiotensin-converting enzyme 2 3
- Bromodomain-containing protein 2 3
- Bromodomain testis-specific protein 3
- Protein polybromo-1 2
- Bromodomain-containing protein 8 2
- Potassium voltage-gated channel subfamily H member 2 2
- Transcription intermediary factor 1-alpha 2
- ATPase family AAA domain-containing protein 2B 1
- Transcription initiation factor TFIID subunit 1-like 1
- Bromodomain and WD repeat-containing protein 1 1
- Bromodomain adjacent to zinc finger domain protein 2A 1
- Peregrin 1
- Bromodomain adjacent to zinc finger domain protein 2B 1
- Nucleosome-remodeling factor subunit BPTF 1
- Bromodomain and PHD finger-containing protein 3 1
- Bromodomain-containing protein 1 1
- E3 ubiquitin-protein ligase TRIM33 1
- Histone acetyltransferase p300 1
- Transcription activator BRG1 1
- ATPase family AAA domain-containing protein 2 1
- Chromatin remodeling regulator CECR2 1
- CREB-binding protein 1
- Histone acetyltransferase KAT2B 1
- Histone acetyltransferase KAT2A 1
- Transcription initiation factor TFIID subunit 1 1
- Bromodomain-containing protein 7 1
- Probable global transcription activator SNF2L2 1
- Bromodomain-containing protein 9 1
Publications 2▿
- J Med Chem (2021) 189
- J Med Chem 63: 7186-7210 (2020) 70
Institutions 2▿
- University of Illinois At Chicago 189
- University Of Illinois At Chicago 70
Affinity: 1 to 1.0E+6 nM▿
- IC50 121
- Kd 130
- EC50 3
- Affinity ≤ nM
Xtal structures: 7
Docked structures: 0
Catalog Cmpds: 6