TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 229nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 282nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 291nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 327nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 331nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 383nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 665nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 2.83E+3nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataIC50: 3.62E+3nMAssay Description:Displacement of [5,6-3H]-nicotinic acid from recombinant human HCA2 receptor expressed in Flp-IN HEK cell membranes after 2 hrs by microbeta counting...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 900nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.90E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 4.50E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 4.10E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 3.60E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 8.30E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 4.10E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 2.74E+4nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 6.80E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 6.30E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 5.80E+3nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 5.16E+4nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 2.63E+4nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.25E+4nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Latvian Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 3.64E+4nMAssay Description:Agonist activity at human HCA2 receptor expressed in Flp-In-293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 5.20E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 5.20E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.24E+4nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 3.90E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 7.00E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 3.73E+4nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Institute Of Organic Synthesis
Curated by ChEMBL
Institute Of Organic Synthesis
Curated by ChEMBL
Affinity DataEC50: 3.60E+3nMAssay Description:Modulation of BCRP1 mediated drug efflux in mitoxantrone-resistant human MES-SA cells assessed as accumulation of hoechst 33342 incubated for 15 mins...More data for this Ligand-Target Pair