TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Antagonist activity at human EP3c receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced calcium mobilization after 24 hrs by ...More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Binding affinity to recombinant oxytocin receptorMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.01nMAssay Description:Binding affinity to human EP3More data for this Ligand-Target Pair
Affinity DataKi: 5.01nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Antagonist activity at human EP3c receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced calcium mobilization after 24 hrs by ...More data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Inhibition of rat EP3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Antagonist activity at human EP3 receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced intracellular calcium mobilization by ...More data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 7.80nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Antagonist activity at human EP3c receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced calcium mobilization after 24 hrs by ...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity to human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
Affinity DataKi: 15.8nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair
Affinity DataKi: 19.9nMAssay Description:Antagonist activity at human EP3c receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced calcium mobilization after 24 hrs by ...More data for this Ligand-Target Pair
Affinity DataKi: 19.9nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human EP3 receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced intracellular calcium mobilization by ...More data for this Ligand-Target Pair
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity to recombinant oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium concentrati...More data for this Ligand-Target Pair